Results 121 to 130 of about 2,002,030 (303)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Jurnal Sosiologi Andalas: This article describes the research findings behind the implementation of ETLE in motorists’ understanding and the causes of motorists' non-compliance with the implementation of CCTV-based ETLE (Electronic Traffic Law Enforcement) in Bengkulu City. The
Putra Michael Sijabat +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
پزشکی بالینی ابن سینا, 2018 Background and Objective: Car accidents are the second leading cause of mortality in Iran. For safe driving, drivers require minimum acceptable visual acuity.
Nooshin Bazzazi +4 more
doaj
Cogent Food & AgricultureWaste management (WM) is fundamental for sustainable development; however, practices and approaches vary between developed and developing countries. Costa Rica belongs to the latter group, and although the country has shown a steady commitment toward ...
Mercedes Montero-Vega +3 more
doaj +1 more source
The Identification of Key Factors and drivers Affecting Potential Soft War scenarios against the Armed Forces of Iran [PDF]
آیندهپژوهی دفاعی, 2018 In the present era, the framework of the discourse of war has undergone major changes; this has led the strategies of the enemies, especially the United States, to shift towards intelligent approaches in the context of soft war and the armed forces of ...
hamid hemmat, Ali Farhadi
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
LandThe rapid expansion of cropland in Cambodia, the world’s seventh-largest rice exporter, has created an imbalance in land use structure. However, there is a lack of quantitative investigation of the loss of ecological land as a result of the expansion of ...
Danni Su +7 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source