Results 41 to 50 of about 312,451 (266)

Impact of Japan's 2024 Physician Work‐Style Reform on Pediatric Hematology–Oncology: Educational Implications in a 2‐Year Survey

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Japan's 2024 physician work‐style reform introduced legally binding limits on physicians’ working hours, but its impact on education and workforce sustainability in pediatric hematology–oncology (PHO) remains unclear. Procedure We conducted a repeated cross‐sectional study with structured quantitative items and free‐text responses ...
Kiyohiko Kaizu   +7 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Development of a Representative EV Urban Driving Cycle Based on a k-Means and SVM Hybrid Clustering Algorithm

open access: yesJournal of Advanced Transportation, 2018
This paper proposes a scientific and systematic methodology for the development of a representative electric vehicle (EV) urban driving cycle. The methodology mainly includes three tasks: test route selection and data collection, data processing, and ...
Xuan Zhao   +5 more
doaj   +1 more source

Construction of Private Passenger Vehicles Travel Characteristics in Harbin

open access: yesJournal of Harbin University of Science and Technology, 2017
GPS was used to collect driving date of private passenger vehicles in actual operation in Harbin.Travel characteristics of private passenger vehicles in Harbin downtown were built,including travel mileagedistribution,travel frequency distribution and ...
CHEN Han, WU Xiao-gang
doaj   +1 more source

Simulation-Based Comparative Assessment of a Multi-Speed Transmission for an E-Retrofitted Heavy-Duty Truck

open access: yesEnergies, 2022
Electric retrofitting (e-retrofitting) is a viable option for accelerating the renewal of heavy-duty vehicle fleets to reduce the related emissions. We introduce a simulation-based assessment of e-retrofitting strategies for heavy-duty vehicles.
Milla Vehviläinen   +7 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Demagnetization Analysis of Interior Permanent Magnet Synchronous Motors Under Realistic Vehicle Driving Conditions

open access: yesIEEE Access
Electric vehicles primarily use interior permanent magnet synchronous motors (IPMSMs) as traction motors. Although IPMSMs are powerful and efficient, their neodymium-based permanent magnets are susceptible to demagnetization under high-temperature ...
Yun-Jin Yang, Dae-Han Kim, Yong-Min You
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Construction of Battery Electric Vehicle Driving Cycles Based on Improved Grey Wolf Optimized K-Means Clustering: A Case Study for Qingdao, China

open access: yesWorld Electric Vehicle Journal
Standardized driving cycles often inadequately represent the driving patterns specific to a particular city, and variations in vehicle types within the same city further contribute to discrepancies in driving cycles.
Rui Liang, Junnan He, Pei Lu
doaj   +1 more source

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