Results 71 to 80 of about 1,723,395 (300)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ghost sign for Sid Mottram Cycles on the corner of Wolverton Road and Narborough Road, 2023.
, 2023 Ghost sign for Sid Mottram Cycles made up of two parts. On the left, the sign reads 'Sid Mottram / Racing & Touring Cycles', and on the right, the sign reads 'Falcon. Dawes. Holdsworth. Claud Butler. Sun & Raleigh Cycles'.
Hyde, Colin
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An investigation on the effect of driver style and driving events on energy demand of a PHEV [PDF]
, 2012 Environmental concerns, security of fuel supply and CO2 regulations are driving innovation in the automotive industry towards electric and hybrid electric vehicles.
McGordon, Andrew +5 more
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Driving Behavior Categorization and Models for Generation of Mission-based Driving Cycles
, 2019 The concept of mission-based driving cycles has been introduced as an efficient way of generating driving cycles with desired characteristics for data-driven development of vehicle powertrains.
Frisk, Erik, +5 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Other title: Teen safe driving in Connecticut
, 2012 Annual; "Annual Report on Effectiveness of Connecticut's Teen Driving Laws.
core
, 2023 A methodology for the generation of representative driving cycles is proposed and evaluated. The proposed method combines traffic simulation and driving behavior modeling to generate mission-based driving cycles.
Frisk, Erik, +2 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Protocol to evaluate methods designed for the construction of representative driving cycles
Revista Facultad de Ingeniería Universidad de AntioquiaMultiple methods have been developed to construct driving cycles. However, a procedure to verify the ability of those methods to construct driving cycles that accurately represent local driving patterns has yet to be established.
Michael Daniel Giraldo-Galindo +2 more
doaj +1 more source