Results 71 to 80 of about 1,646,609 (294)

The measurement of vehicular driving cycle within the city of Edinburgh

, 2001
In this paper, the development of a driving cycle for the urban area of the city of Edinburgh is presented. The driving cycle was obtained from recorded data in actual traffic conditions, using the car chase technique.
Muneer, Tariq, Kubie, Jorge, Kirby, Howard, Hunter, J, Esteves-Booth, A   +4 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Real-world driving cycles for measuring cars pollutant emissions - Part A: The ARTEMIS European driving cycles

, 2009
In the frame of the ARTEMIS European research project, a compilation and synthesis of previous works has been considered to derive a set of reference real-world driving cycles.
Andre, Michel
core   +5 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Validating on-the-limit properties of a driving simulator

, 2014
The paper describes a validation model for both subjective and objective comparison of on-the-limit properties of a driving simulator. VTI moving base driving simulator, SIM III, has been used with three different versions of VTI’s vehicle model, for ...
Kharrazi, Sogol, Eriksson, Olle, Hjort, Mattias, Hjälmdahl, Magnus, Andersson Hultgren, Jonas   +4 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Cycling of biogenic elements drives biogeochemical gold cycling [PDF]

Earth-Science Reviews, 2019
Abstract Microorganisms are key-drivers of carbon-, nitrogen-, sulfur- and metal cycling on Earth. Through their metabolic activities they directly and indirectly link element cycles. This leads to the cycling of elements through the Earth’s ecosystems from/to the atmosphere to/from the lithosphere. Gold (Au) is a rare, redox-active, noble transition
Santonu Kumar Sanyal, Jeremiah Shuster, Frank Reith   +2 more
openaire   +2 more sources

Proposal of a dynamic performance index to analyze driving pattern effect on car emissions [PDF]

, 2009
The contributions of driver behaviour as well as surrounding infrastructure are decisive on pollutant emissions from vehicles in real traffic situations.
Casanova Kindelán, Jesús, Fonseca González, Natalia Elizabeth, Espinosa Zapata, Felipe   +2 more
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source