Results 51 to 60 of about 1,646,609 (294)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Predictive Finite Speed-Set MRAS for Robust Sensorless Control of PMSM Drives in Electric Vehicles Under Driving Cycle

open access: yesMachines
Model reference adaptive system (MRAS)-based techniques are widely used for sensorless speed estimation in permanent magnet synchronous motor (PMSM) drives.
Amr A. Saleh   +3 more
doaj   +1 more source

The Construction of Xi’an Urban Bus Driving Cycle: A Case Study

open access: yesFuture Transportation, 2023
At present, there are many methods to construct a vehicle driving cycle, such as the micro-trip-based method and the Markov chain method. Different methods have different advantages and disadvantages.
Yaohua Li   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Minimizing Energy Consumption and Powertrain Cost of Fuel Cell Hybrid Vehicles with Consideration of Different Driving Cycles and SOC Ranges

open access: yesEnergies, 2022
Hydrogen consumption is an important performance indicator of fuel cell hybrid vehicles (FCHVs). Previous studies have investigated fuel consumption minimization both under different driving cycles and using various power management strategies.
Yang Gao   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Other title: Teen safe driving in Connecticut

open access: yes, 2014
Annual; "Annual Report on Effectiveness of Connecticut's Teen Driving Laws.

core   +1 more source

A Novel Method of Developing Driving Cycle for Electric Vehicles to Evaluate the Private Driving Habits

open access: yesIEEE Access, 2021
As one of important implications on electric vehicles, driving cycles are recognized as essential components for evaluating the comprehensive performances and they have drawn much attention for research.
Fei Chen   +7 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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