Results 41 to 50 of about 1,723,395 (300)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

The ecology of urban driving II—driving cycles across a city: Their validation and implications

open access: yes, 1992
Homogeneous urban areas defined through an urban ecology approach are used to sample traffic patterns for a series of cross city driving cycles in Perth, Western Australia.
Kenworthy, J.R.   +5 more
core   +2 more sources

Standardized Comparison of 40 Local Driving Cycles: Energy and Kinematics

open access: yesEnergies, 2020
Local driving cycles (LDCs) capture local traffic characteristics, while standard driving cycles (SDCs) compare vehicles in distinct regions. There is a plethora of LDCs, raising the question as to how distinct they are.
Guilherme Medeiros Soares de Andrade   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

The Construction of Xi’an Urban Bus Driving Cycle: A Case Study

open access: yesFuture Transportation, 2023
At present, there are many methods to construct a vehicle driving cycle, such as the micro-trip-based method and the Markov chain method. Different methods have different advantages and disadvantages.
Yaohua Li   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Determination of the Performance Characteristics of a Traction Battery in an Electric Vehicle

open access: yesWorld Electric Vehicle Journal
Electric vehicles are the most innovative and promising area of the automotive industry. The efficiency of a traction battery is an important factor in the performance of an electric vehicle. This paper presents a mathematical model of an electric truck,
Boris V. Malozyomov   +7 more
doaj   +1 more source

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