Results 61 to 70 of about 1,723,395 (300)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Test-retest reliability of simulated driving performance: A pilot study [PDF]

, 2013
Twenty-seven volunteers completed three simulated driving tests to determine test-retest reliability of performance on a low-cost, fixed-base computerized driving simulator.
Leveritt, Michael, Irwin, Chris, Desbrow, Ben, Shum, David   +3 more
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

A Predictive Finite Speed-Set MRAS for Robust Sensorless Control of PMSM Drives in Electric Vehicles Under Driving Cycle

Machines
Model reference adaptive system (MRAS)-based techniques are widely used for sensorless speed estimation in permanent magnet synchronous motor (PMSM) drives.
Amr A. Saleh, Mohammed A. Hassan, Tarek M. Said, Mahmoud M. Adel   +3 more
doaj   +1 more source

Construction of the Kielce Driving Cycles [PDF]

, 2016
W artykule zaprezentowano metodologię konstrukcji cykli jazdy. Ustandaryzowane cykle jazdy, wykorzystywane m.in. do badań homologacyjnych, realizowane są w warunkach laboratoryjnych i nie odzwierciedlają rzeczywistych warunków eksploatacji, przez co ...
Zielińska, D., Szumska, E., Pawełczyk, M.   +2 more
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Development of a Representative EV Urban Driving Cycle Based on a k-Means and SVM Hybrid Clustering Algorithm

Journal of Advanced Transportation, 2018
This paper proposes a scientific and systematic methodology for the development of a representative electric vehicle (EV) urban driving cycle. The methodology mainly includes three tasks: test route selection and data collection, data processing, and ...
Xuan Zhao, Qiang Yu, Jian Ma, Yan Wu, Man Yu, Yiming Ye   +5 more
doaj   +1 more source

Data Processing Framework for Development of Driving Cycles with Data from SHRP 2 Naturalistic Driving Study

, 2017
In the modeling of vehicle operation costs, a driving cycle is a representative speed–time profile to describe the speed–acceleration pattern of a specific road scenario.
Yuan Sun, Hao Xu, Jianqing Wu, Elie Y. Hajj, Xinli Geng   +4 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Cycling of biogenic elements drives biogeochemical gold cycling [PDF]

Earth-Science Reviews, 2019
Abstract Microorganisms are key-drivers of carbon-, nitrogen-, sulfur- and metal cycling on Earth. Through their metabolic activities they directly and indirectly link element cycles. This leads to the cycling of elements through the Earth’s ecosystems from/to the atmosphere to/from the lithosphere. Gold (Au) is a rare, redox-active, noble transition
Santonu Kumar Sanyal, Jeremiah Shuster, Frank Reith   +2 more
openaire   +2 more sources