Results 91 to 100 of about 182,013 (307)
Driving Forces of European Landscape Change
This master's thesis examines driving forces of landscape change in the Wadden Sea region. The region is a UNESCO World Natural Heritage site and encompasses North Sea coasts of Denmark, Germany and the Netherlands.
MATT, Gordon
core
DRIVING FORCES FOR URBAN DESIGN AND CITIES FUNCTIONALITY [PDF]
The global population is mostly concentrated in cities, created as areas that face many challenges such as economic, social or environmental ones. The impact of urban areas is felt not only in cities but also in other regions so well designed and well ...
Madalina DOCIU +2 more
doaj
Exploring the Factors Driving Changes in Farmland within the Tumen/Tuman River Basin
Understanding farmland changes and their mechanisms is important for food security and sustainable development. This study assesses the farmland changes and their drivers within the Tumen River of China and the Tuman River within the Democratic People ...
Cholhyok Kang +5 more
doaj +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Beyond the Greenwash: Institutional Forces Driving universitySDG Reporting
Purpose The purpose of this study is to examine the disclosures on Sustainable Development Goals (SDGs) by the New Zealand (NZ) university sector, with the aim of analysing the extent, content and quality of reporting.
Ali, Irshad +3 more
core +1 more source
1. We studied driving forces shaping phytoplankton assemblages in two subtropical plateau lakes with contrasting trophic status, the oligotrophic deep Lake Fuxian and the eutrophic shallow Lake Xingyun. 2.
Xie, P, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol China, Donghu Expt Stn Lake Ecosyst, Wuhan 430072, Peoples R China +5 more
core +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source

