Results 91 to 100 of about 428,792 (296)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Wellcome Open Research, 2017 Background: Many powered wheelchair users find their medical condition and their ability to drive the wheelchair will change over time. In order to maintain their independent mobility, the powered chair will require adjustment over time to suit the user ...
Michael Gillham +3 more
doaj +1 more source
Secure access control by means of human stress detection
, 2011 This paper proposes a stress detection system based on fuzzy logic and the physiological signals heart rate and galvanic skin response. The main contribution of this method relies on the creation of a stress template, collecting the behaviour of previous
Bailador del Pozo, Gonzalo +8 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Wellcome Open Research, 2018 Background: Many powered wheelchair users find their medical condition and their ability to drive the wheelchair will change over time. In order to maintain their independent mobility, the powered chair will require adjustment over time to suit the user ...
Michael Gillham +3 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The role of expert evaluation for microsleep detection
Current Directions in Biomedical Engineering, 2015 Recently, it has been shown by overnight driving simulation studies that microsleep density is the only known sleepiness indicator which rapidly increases within a few seconds immediately before sleepiness related crashes.
Golz M. +4 more
doaj +1 more source
Implementing an Adaptive Algorithm for Hybrid EVs: Recognising Driving Patterns with Artificial Intelligence [PDF]
E3S Web of ConferencesThis review article delves into the enhancement of fuel efficiency in hybrid electric vehicles (HEVs) through the use of adaptive algorithms for precise driving pattern recognition.
Sikka Rishi +3 more
doaj +1 more source
, 2021 S.26-40Living in a complex world like ours makes it unacceptable that a practical implementation of a machine learning system assumes a closed world. Therefore, it is necessary for such a learning-based system in a real world environment, to be aware of ...
Bayer, Jens +5 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source