Results 31 to 40 of about 116,817 (311)

Classification and Evaluation of Driving Behavior Safety Levels: A Driving Simulation Study

IEEE Open Journal of Intelligent Transportation Systems, 2022
The road traffic safety situation is severe worldwide and exploring driving behavior is a research hotspot since it is the main factor causing road accidents.
Kui Yang, Christelle Al Haddad, George Yannis, Constantinos Antoniou   +3 more
doaj   +1 more source

Development of Local Path Planning Using Selective Model Predictive Control, Potential Fields, and Particle Swarm Optimization

Robotics
This paper focuses on the real-time obstacle avoidance and safe navigation of autonomous ground vehicles (AGVs). It introduces the Selective MPC-PF-PSO algorithm, which includes model predictive control (MPC), Artificial Potential Fields (APFs), and ...
Mingeuk Kim, Minyoung Lee, Byeongjin Kim, Moohyun Cha   +3 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Examining the Effects of HMDs/FSDs and Gender Differences on Cognitive Processing Ability and User Experience of the Stroop Task-Embedded Virtual Reality Driving System (STEVRDS)

IEEE Access, 2020
The advent of virtual reality technology has provided a new approach for assessing and training cognitive processing ability, with the design of simulations used to replicate real events in everyday lives.
Chen-Wei Chang, Mengtong Li, Shih-Ching Yeh, Yijing Chen, Albert Rizzo   +4 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Vehicle Driving Safety of Underground Interchanges Using a Driving Simulator and Data Mining Analysis

Infrastructures
In the process of driving in an underground interchange, drivers are faced with many challenges, such as being in a closed space, visual changes alternating between light and dark conditions, complex road conditions in the confluence section, and dense ...
Zhen Liu, Qifeng Yang, Anlue Wang, Xingyu Gu   +3 more
doaj   +1 more source

The Effect of Driving Style on Responses to Unexpected Vehicle Cyberattacks

Safety, 2023
Vehicle cybersecurity is a serious concern, as modern vehicles are vulnerable to cyberattacks. How drivers respond to situations induced by vehicle cyberattacks is safety critical.
Fangda Zhang, Meng Wang, Jah’inaya Parker, Shannon C. Roberts   +3 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source