Results 51 to 60 of about 2,359,063 (339)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Back on the Road: Comparing Cognitive Assessments to Driving Simulators in Moderate to Severe Traumatic Brain Injuries

open access: yesBrain Sciences, 2022
Objective: To compare established clinical outcome assessments for predicting behind the wheel driving readiness and driving simulator results across age groups and in traumatic brain injury.
Debra S. Ouellette   +2 more
doaj   +1 more source

Vestibular Feedback on a Virtual Reality Wheelchair Driving Simulator: A Pilot Study

open access: yesIEEE/ACM International Conference on Human-Robot Interaction, 2020
Autonomy and the ability to maintain social activities can be challenging for people with disabilities experiencing reduced mobility. In the case of disabilities that impact mobility, power wheelchairs can help such people retain or regain autonomy ...
Guillaume Vailland   +5 more
semanticscholar   +1 more source

A framework for simulation of surrounding vehicles in driving simulators

open access: yesACM Transactions on Modeling and Computer Simulation, 2008
This article describes a framework for generation and simulation of surrounding vehicles in a driving simulator. The proposed framework generates a traffic stream, corresponding to a given target flow and simulates realistic interactions between vehicles.
Johan Janson Olstam   +3 more
openaire   +4 more sources

Control of a Dynamic Driving Simulator: Time-Variant Motion Cueing Algorithms and Prepositioning [PDF]

open access: yes, 2006
This thesis mainly addresses the task to provide the driver of a dynamic driving simulator with the same motion cues as would occur in reality. The DLR Driving Simulator, which is the subject matter of this thesis, uses a hexapod motion platform to ...
Weiß, Cornelius
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Integration of a driving simulator and a traffic simulator case study: Exploring drivers' behavior in response to variable message signs

open access: yesIATSS Research, 2017
For the first time, a driving simulator has been integrated with a traffic simulator at the network level to allow subjects to drive in a fairly realistic environment with a realistic traffic flow and density. A 10 mi2 (25 km2) network was developed in a
Mansoureh Jeihani   +2 more
doaj   +1 more source

Vibrations in dynamic driving simulator: Study and implementation [PDF]

open access: yes, 2013
This paper shows the effect of adding vibrations in a car cabin during driving simulation on driver perception. Actually, current dynamic driving simulators induce the simulator sickness and it still difficult for the driver to project himself in the ...
MERIENNE, Frédéric   +3 more
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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