Results 31 to 40 of about 638,146 (260)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Analysis of Sea‑Based Landing Dynamics of Reusable Landing Vehicle Considering Mechanism Flexibility

open access: yesTransactions of Nanjing University of Aeronautics and Astronautics
Vertical landing and recovery of a launch vehicle at sea can further reduce the launch cost of commercial space-flight, so this paper investigates the issue of reusable launch vehicle landing at sea. A vehicle landing dynamics model considering mechanism
YANG Shaofei   +3 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

An Improved Reduced‑Mass Method for Drop Test of Truck‑Beam Landing Gears

open access: yesNanjing Hangkong Hangtian Daxue Xuebao
Truck-beam landing gears usually face vertical velocity distortion of the drop test basket during traditional reduced-mass method drop tests, leading to deviations in dynamic response.
LI Xinran   +4 more
doaj   +1 more source

THE INFLUENCE OF THE APPLICATED ON THE FILTERING PAPER MOTOR OIL QUANTITY ON ITS INDICATORS’ EVALUATION

open access: yesВестник СибАДИ, 2018
The most common method of controlling the motor oil detergent-dispersant properties is the «drop sample» method (the applying process of the engine  oil drop to the filter paper -»blue tape» and the calculating process of the  drop sample with an oil ...
A. P. Zhigadlo   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Analysis of spin-up and spring back loads of landing gear based on slip rate

open access: yesHangkong gongcheng jinzhan
The landing gear spin-up and spring back loads are the important part of the aircraft landing load. In order to effectively analyze the spin-up and spring back loads of the landing gear in the preliminary design stage,the two-wheel strut landing gear ...
WU Ming   +3 more
doaj   +1 more source

Experimental and Numerical Investigation of Steel Sections under Impact Effect

open access: yesGrađevinar, 2021
Experimental and numerical behaviour of steel test specimens with various types of joints is investigated in this study. A drop weight test setup with necessary test equipment is used for this purpose.
Engin Gücüyen   +3 more
doaj   +1 more source

Influence of Freeze-Thaw Aging on the Impact Performance of Damped Carbon Fiber Reinforced Plastics for Automotive Applications

open access: yesApplied Sciences, 2022
The increasing use of composite materials in the automotive field requires more attention with regards to the appearance of noise, vibration and harshness (NVH) study in cars construction.
Enrico Virgillito   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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