Results 61 to 70 of about 1,385,030 (235)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Relative dispersion (ɛ) is a key expression used to parameterize various cloud processes in global circulation models (GCMs) and meteorological mesoscale models.
Suying Yang +4 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Determination of nozzle quality ratings based on macroscopic and microscopic parameters generally requires the use of separate measurement methods in research.
Dariusz Lodwik, Mariusz Koprowski
doaj +1 more source
Bridging the condensation–collision size gap: a direct numerical simulation of continuous droplet growth in turbulent clouds [PDF]
In most previous direct numerical simulation (DNS) studies on droplet growth in turbulence, condensational growth and collisional growth were treated separately.
S. Chen, M.-K. Yau, P. Bartello, L. Xue
doaj +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
The importance of aerosol and droplet microphysics for the properties and life cycle of radiation fog in the Po Valley [PDF]
Employing high-resolution Large Eddy Simulation (LES) coupled with interactive aerosol and cloud microphysics schemes, this study investigates the influence of aerosol and droplet microphysics on the life cycle and properties of wintertime radiation fog ...
H. Ding +26 more
doaj +1 more source
Droplet spectrum quality is essential to effectively control crop pests and diseases. This study aimed to characterize the droplet uniformity of the eight most popular flat-fan nozzles used by Brazilian farmers and relate it to their spraying quality ...
Fabiano Griesang +5 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source

