Results 51 to 60 of about 2,380,969 (281)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Materials & Design, 2019 The effects of arc bubble behaviors and characteristics on droplet transfer are observed with an in-situ X-ray imaging method. The changes in the force acting on the droplet are analyzed at three distinct stages of arc bubble in one life cycle.
Hao Chen +5 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Lattice Boltzmann simulation of droplet behaviour in microfluidic devices [PDF]
, 2009 We developed a lattice Boltzmann model to investigate the droplet dynamics in microfluidic devices. In our model, a stress-free boundary condition was proposed to conserve the total mass of flow system and improve the numerical stability for flows with ...
Zhang, Yonghao, Liu, Haihu
core +3 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
ISME Communications, 2022 Conjugal plasmids constitute a major engine for horizontal gene transfer in bacteria, and are key drivers of the spread of antibiotic resistance, virulence, and metabolic functions.
Tomer Orevi +2 more
doaj +1 more source
Metals, 2021 Hybrid laser arc welding (HLAW) features advantages such as higher welding speed and gap tolerance as well as smaller welding deformation and heat-affected zone than arc welding.
Leilei Wang +3 more
doaj +1 more source
Hydrodynamic structures of droplets in square micro-channels [PDF]
, 2008 This paper reports on numerical simulations of the hydrodynamics inside droplets in rectangular micro-channels. We use a finite-volume/front-capturing method that allows us to perform two- and three-dimensional simulations with a reasonable cost.
Prat, Laurent E. +5 more
core +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Online Detection of Keyhole Status in a Laser-MIG Hybrid Welding Process
Metals, 2022 During laser-metal inert gas (MIG) hybrid welding, a large amount of welding status information is generated in droplet transfer, keyhole and molten pool.
Xi’an Fan +3 more
doaj +1 more source