Results 1 to 10 of about 6,765,531 (294)

Bone-targeted mitochondrial delivery via magnetic-temperature responsive artificial cells for repairing age-related fractures [PDF]

Frontiers in Pharmacology
BackgroundAge-related bone diseases, such as osteoporosis and degenerative joint disorders, pose a significant global health challenge, leading to over 9 million fractures annually, which not only diminishes quality of life but also imposes a substantial
Shihao Nie, Yue Yu, Rong Yan, Taoran Liu, Yue Du, Zhuojing Luo, Zhuojing Luo, Shengyou Li, Shengyou Li, Jinghui Huang   +9 more
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Preservation of Complex Multiphase Architectures in Polymer‐Based Artificial Cells by Photo‐Crosslinking [PDF]

Advanced Science
Nature utilizes phase separation to create biomolecular condensates which spatially organize cellular components. In artificial cells, however, mimicking the structure of cellular multiphase systems is challenging.
Madelief A. M. Verwiel, Alexander B. Cook, Yiǧitcan Sümbelli, Nadia A. Erkamp, Jan C. M. van Hest   +4 more
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Editorial: Innovative medical technology based on artificial cells, including its different configurations [PDF]

Frontiers in Medical Technology, 2023
Thomas Ming Swi Chang
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Synthetic Cells Revisited: Artificial Cell Construction Using Polymeric Building Blocks [PDF]

Advanced Science
The exponential growth of research on artificial cells and organelles underscores their potential as tools to advance the understanding of fundamental biological processes.
Viviana Maffeis, Lukas Heuberger, Anamarija Nikoletić, Cora‐Ann Schoenenberger, Cornelia G. Palivan   +4 more
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A polymer–lipid membrane artificial cell nanocarrier containing enzyme–oxygen biotherapeutic inhibits the growth of B16F10 melanoma in 3D culture and in a mouse model

Artificial Cells, Nanomedicine, and Biotechnology, 2021
Melanoma is a deadly skin cancer. Surgery is effective for early stages but there may be remnant cells. Treatments of later stages are associated with severe side effects. Moreover, a dangerous type of melanoma cannot be detected early enough for surgery.
Yun Wang, Thomas Ming Swi Chang
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Artificial Cell Encapsulation for Biomaterials and Tissue Bio-Nanoengineering: History, Achievements, Limitations, and Future Work for Potential Clinical Applications and Transplantation

Journal of Functional Biomaterials, 2021
Pancreatic β-cell loss and failure with subsequent deficiency of insulin production is the hallmark of type 1 diabetes (T1D) and late-stage type 2 diabetes (T2D).
Armin Mooranian, Melissa Jones, Corina Mihaela Ionescu, Daniel Walker, Susbin Raj Wagle, Bozica Kovacevic, Jacqueline Chester, Thomas Foster, Edan Johnston, Jafri Kuthubutheen, Daniel Brown, Momir Mikov, Hani Al-Salami   +12 more
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Droplet Microfluidics for Tumor Drug‐Related Studies and Programmable Artificial Cells

Global Challenges, 2021
Anticancer drug development is a crucial step toward cancer treatment, that requires realistic predictions of malignant tissue development and sophisticated drug delivery. Tumors often acquire drug resistance and drug efficacy, hence cannot be accurately
Pantelitsa Dimitriou, Jin Li, Giusy Tornillo, Thomas McCloy, David Barrow   +4 more
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Formation of Giant Unilamellar Vesicles Assisted by Fluorinated Nanoparticles

Advanced Science, 2023
In the quest to produce artificial cells, one key challenge that remains to be solved is the recreation of a complex cellular membrane. Among the existing models, giant unilamellar vesicles (GUVs) are particularly interesting due to their intrinsic ...
Jorik Waeterschoot, Willemien Gosselé, Hojjat Alizadeh Zeinabad, Jeroen Lammertyn, Erin Koos, Xavier Casadevall i Solvas   +5 more
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INDIVIDUAL STABILITY OF STEREOTYPES OF IMMUNE REACTING AND MODERN POSSIBILITIES OF THEIR DIAGNOSTIC IN ORGAN TRANSPLANTATION (IMMUNE-PHYSIOLOGICAL ANALYSIS OF A PROBLEM)

Вестник трансплантологии и искусственных органов, 2013
The authors prove variants of immune reacting of an human organism in organ transplantation by existence of individual specific programs of reacting on alloantigens which, using natural activatory and inhibitory mecha- nisms, form various degree of ...
N. A. Onischenko, S. D. Artamonov, M. E. Krasheninnikov, L. V. Bashkina, A. O. Nicolskaya   +4 more
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Investigation of Genipin Cross-Linked Microcapsule for Oral Delivery of Live Bacterial Cells and Other Biotherapeutics: Preparation and In Vitro Analysis in Simulated Human Gastrointestinal Model

International Journal of Polymer Science, 2010
Oral therapy utilizing engineered microorganisms has shown promise in the treatment of many diseases. By microencapsulation, viable cells can overcome the harsh gastrointestinal (GI) environment and secrete needed therapeutics into the gut.
Hongmei Chen, Wei Ouyang, Christopher Martoni, Fatemeh Afkhami, Bisi Lawuyi, Trisna Lim, Satya Prakash   +6 more
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