Results 51 to 60 of about 22,218 (269)

Introduction of variability in pantograph-catenary dynamic simulations [PDF]

open access: yes, 2013
Currently, pantograph-catenary dynamic simulations codes are mainly based on deterministic approaches. However, the contact force between catenary and pantograph depends on many key parameters that are not always quantified precisely.
BALMES, Etienne   +3 more
core   +3 more sources

Quantum key distribution using non-classical photon number correlations in macroscopic light pulses [PDF]

open access: yes, 2001
We propose a new scheme for quantum key distribution using macroscopic non-classical pulses of light having of the order 10^6 photons per pulse. Sub-shot-noise quantum correlation between the two polarization modes in a pulse gives the necessary ...
A. C. Funk   +11 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Reducing the expense of ear wax [PDF]

open access: yes, 2006
Ear wax is one of the commonest presenting complaints both in Ear Nose and Throat surgery and in General Practice. The commonest treatment by far given for this condition is Arachis oil (Cerumol®).
Borg Xuereb, Hermann K.   +1 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Resilience testing device Patent [PDF]

open access: yes, 1971
Automated ball rebound resilience test equipment for determining viscoelastic properties of ...
Jellison, J. C., Weitzel, D. H.
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Effect of the farming intensification on health-promoting compounds in the meat of the Mediterranean mussel Mytilus galloprovincialis

open access: yesAquaculture Reports
This study investigated the effect of increasing levels of farming intensification on some health-promoting compounds present in the meat of the Mediterranean mussel Mytilus galloprovincialis in the Northern Coastal Area of Gargano, Italy, during the ...
Antonella della Malva   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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