Results 101 to 110 of about 525,943 (299)
, 2015 National audienceThe period of time from now to 2050 is required for designing varieties able to cope with climate changes. Phenotyping is the main limiting step, now that genotyping has become an almost routine activity.
Tardieu, Francois, F.
core
Thermocapillary migration and interaction of two nondeformable drops
, 2011 A numerical study on the interaction of two spherical drops in the thermocapillary migration is presented in the microgravity environment. Finite-difference methods are adopted. The interfaces of the drops are captured by the front-tracking technique. It
高鹏 +4 more
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
, 2020 Here we extend the results in Gordillo et al. (J. Fluid Mech., vol. 866, 2019, pp. 298–315), where the spreading of drops impacting perpendicularly a solid wall was analysed, to predict the time-varying flow field and the thickness of the liquid film ...
Riboux, Guillaume Maurice +2 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Drop Dissolution Intensified by Acoustic Levitation
MicromachinesAcoustic levitation can provide significant benefits for many fundamental research questions. However, it is important to consider that the acoustic field influences the measurement environment.
Jan-Paul Ruiken +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Drop-charge correlations for polydisperse electrostatically atomized liquid sprays
, 2004 In many applications liquid sprays are atomized using electrostatic methods, and typically these spray plumes containing drops that have a range of diameters.
Wong, M.C.Y., Shrimpton, J.S.
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