Results 111 to 120 of about 1,590,610 (300)
Ophthalmic and anesthetic evaluation of topical 1% tetracaine and 0.5% proparacaine in dogs
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2011 The aim of this study was to establish the action of 1% tetracaine eye drops in combination with 0.1% phenylephrine in two different posologies and their effects on the eye compared to the 0.5% proparacaine drops in dogs. 22 animals were divided into two
H.D. Parchen +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Coalescence collision of liquid drops I: Off-center collisions of equal-size drops
AIP Advances, 2011 The Smoothed Particle Hydrodynamics method (SPH) is used here to model off-center collisions of equal-size liquid drops in a three-dimensional space. In this study the Weber number is calculated for several conditions of the droplets dynamics and the ...
Alejandro Acevedo-Malavé +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Coalescence collision of liquid drops II: Off-center collisions of unequal-size drops
AIP Advances, 2011 We applied the Smoothed Particle Hydrodynamics method to simulate for first time in the three-dimensional space the hydrodynamic off-center collisions of unequal-size liquid drops in a vacuum environment.
Alejandro Acevedo-Malavé +1 more
doaj +1 more source
Dynamics of Perfectly Wetting Drops under Gravity
, 2006 We study the dynamics of small droplets of polydimethylsiloxane (PDMS) silicone oil on a vertical, perfectly-wetting, silicon wafer. Interference videomicroscopy allows us to capture the dynamics of these droplets.
A. Oron +5 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
MATEC Web of Conferences, 2018 We have reviewed the known data about mechanisms, conditions, reasons, and characteristics of rebound, coagulation, and explosive disintegration of drops in gas-vapor-droplet streams.
Voytkov Ivan +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source