Results 71 to 80 of about 641,541 (231)

The selectivity and specificity of autophagy in drosophila [PDF]

open access: yes, 2012
Autophagy is a process of cellular self-degradation and is a major pathway for elimination of cytoplasmic material by the lysosomes. Autophagy is responsible for the degradation of damaged organelles and protein aggregates and therefore plays a ...
Chou   +27 more
core   +2 more sources

A common genetic target for environmental and heritable influences on aggressiveness in Drosophila [PDF]

open access: yes, 2008
Environmental and genetic factors can modulate aggressiveness, but the biological mechanisms underlying their influence are largely unknown. Social experience with conspecifics suppresses aggressiveness in both vertebrate and invertebrate species ...
Baier   +33 more
core   +3 more sources

A Simple Immunofluorescence Method to Characterize Neurodegeneration and Tyrosine Hydroxylase Reduction in Whole Brain of a Drosophila Model of Parkinson’s Disease

open access: yesBio-Protocol
Dopaminergic (DAergic) neurodegeneration in the substantia nigra pars compacta of the human brain is the pathological feature associated with Parkinson’s disease (PD).
Rahul Chaurasia   +4 more
doaj   +1 more source

A role for kinesin heavy chain in controlling vesicle transport into dendrites in Drosophila. [PDF]

open access: yes, 2011
The unique architecture of neurons requires the establishment and maintenance of polarity, which relies in part on microtubule-based transport to deliver essential cargo into dendrites.
Goldstein, Lawrence SB   +3 more
core   +2 more sources

Computer-Aided Automated Detection of Gene-Controlled Social Actions of Drosophila [PDF]

open access: yesInternational Conference on Smart Cities at Cambridge 2018, 2019
Gene expression of social actions in Drosophilae has been attracting wide interest from biologists, medical scientists and psychologists. Gene-edited Drosophilae have been used as a test platform for experimental investigation. For example, Parkinson's genes can be embedded into a group of newly bred Drosophilae for research purpose.
arxiv  

Dimensionality-Reduction in the Drosophila Wing as Revealed by Landmark-Free Measure-ments of Phenotype [PDF]

open access: yesarXiv, 2020
Organismal phenotypes emerge from a complex set of genotypic interactions. While technological advances in sequencing provide a quantitative description of an organism's genotype, characterization of an organism's physical phenotype lags far behind. Here, we relate genotype to the complex and multi-dimensional phenotype of an anatomical structure using
arxiv  

Short-term maintenance on a high-sucrose diet alleviates aging-induced sleep fragmentation in drosophila

open access: yesAnimal Cells and Systems, 2021
Sleep is a fundamental behavior in an animal’s life influenced by many internal and external factors, such as aging and diet. Critically, poor sleep quality places people at risk of serious medical conditions.
Sang Hyuk Lee, Eun Young Kim
doaj   +1 more source

Effect of bromocriptine alginate nanocomposite (BANC) on a transgenic Drosophila model of Parkinson's disease

open access: yesDisease Models & Mechanisms, 2016
The effect of bromocriptine, a dopamine agonist, administered in the form of bromocriptine alginate nanocomposite (BANC) was studied on Parkinson's disease (PD) model flies.
Yasir Hasan Siddique   +9 more
doaj   +1 more source

Identification of microtubule-associated proteins in the centrosome, spindle, and kinetochore of the early Drosophila embryo. [PDF]

open access: yes, 1989
We have developed affinity chromatography methods for the isolation of microtubule-associated proteins (MAPs) from soluble cytoplasmic extracts and have used them to analyze the cytoskeleton of the early Drosophila embryo.
Alberts, BM, Field, CM, Kellogg, DR
core  

mRNA active transport in oocyte-early embryo: 3D agent-based modeling [PDF]

open access: yesarXiv, 2023
Axes of polarity (and primary morphogenetic gradients) are established in the oocyte - early embryo through active transport and localization of maternal factors. It is the oocyte - syncytial embryo of Drosophila (D. melanogaster) that is a model object for studying the molecular machinery of such transport systems.
arxiv  

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