Results 71 to 80 of about 913,402 (352)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Eco-synthesized silver nanoparticles from Curcuma longa leaves: Phytochemical and biomedical applications

Next Nanotechnology
Nanotechnology has revolutionized biomedical sciences, with silver nanoparticles (AgNPs) gaining attention for their antimicrobial, antioxidant, and anti-inflammatory properties. However, conventional synthesis methods often involve toxic chemicals.
Sapam Riches Singh, S.J. Akshatha, Megha B. Abbigeri, Akshata Choudhari Padti, Santosh Mallikarjun Bhavi, Sudheendra Rao Kulkarni, Bothe Thokchom, Asmatanzeem Bepari, Ramesh Babu Yarajarla, B.S. Srinath   +9 more
doaj   +1 more source

Analysis of Thisbe and Pyramus functional domains reveals evidence for cleavage of Drosophila FGFs [PDF]

, 2010
Background: As important regulators of developmental and adult processes in metazoans, Fibroblast Growth Factor (FGF) proteins are potent signaling molecules whose activities must be tightly regulated.
Stathopoulos, Angelike, Tulin, Sarah
core   +4 more sources

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Hawaiian Picture‐Winged Drosophila Exhibit Adaptive Population Divergence along a Narrow Climatic Gradient on Hawaii Island [PDF]

, 2019
1. Anthropogenic influences on global processes and climatic conditions are increasingly affecting ecosystems throughout the world. 2. Hawaii Island’s native ecosystems are well studied and local long‐term climatic trends well documented, making these ...
Bellinger, M. Renee, Eldon, Jon, Price, Donald K.   +2 more
core   +2 more sources

JAK/STAT signaling in stem cells and regeneration: from Drosophila to vertebrates

Development, 2019
The JAK/STAT pathway is a conserved metazoan signaling system that transduces cues from extracellular cytokines into transcriptional changes in the nucleus. JAK/STAT signaling is best known for its roles in immunity. However, recent work has demonstrated
Salvador C Herrera, E. Bach
semanticscholar   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source

An evaluation of carbon dots derived from Amaranthus tricolor (L.) leaves for their physicochemical, photoluminescent, and biomedical properties

Discover Applied Sciences
This study explores the synthesis, characterization, and bio-functional potential of carbon dots (CDs) derived from Amaranthus tricolor (AT-CDs). Phytochemical analysis confirmed the presence of bioactive compounds while quantitative assays revealed a ...
Sapam Riches Singh, Santosh Mallikarjun Bhavi, Bothe Thokchom, Megha B. Abbigeri, Akshata Choudhari Padti, Akshata Yadawad, B. P. Harini, Chandramohan Govindasamy, Khalid M. Almutairi, Ramesh Babu Yarajarla   +9 more
doaj   +1 more source

The connectome of the adult Drosophila mushroom body provides insights into function

eLife, 2020
Making inferences about the computations performed by neuronal circuits from synapse-level connectivity maps is an emerging opportunity in neuroscience.
Feng Li, Jack W Lindsey, Elizabeth C Marin, Nils Otto, Marisa Dreher, Georgia Dempsey, Ildiko Stark, Alexander S Bates, Markus William Pleijzier, Philipp Schlegel, Aljoscha Nern, Shin-ya Takemura, Nils Eckstein, Tansy Yang, Audrey Francis, Amalia Braun, Ruchi Parekh, Marta Costa, Louis K Scheffer, Yoshinori Aso, Gregory SXE Jefferis, Larry F Abbott, Ashok Litwin-Kumar, Scott Waddell, Gerald M Rubin   +24 more
doaj   +1 more source

Metabolic control of daily locomotor activity mediated by tachykinin in Drosophila

Communications Biology, 2021
Lee and colleagues report the effect of a high-sucrose diet on Drosophila locomotor activity via DTk-TkR86C neuropeptide signalling. This signalling pattern appears to involve a circadian element, with pacemaker neuron involvement having a possible time ...
Sang Hyuk Lee, Eunjoo Cho, Sung-Eun Yoon, Youngjoon Kim, Eun Young Kim   +4 more
doaj   +1 more source