Results 151 to 160 of about 428,367 (405)

A protein restricted diet induces a stable increased fat storage phenotype in flies

Toxicology Reports, 2023
Background: Scientific evidence has revealed possible confounders in diet induced obesity models of Drosophila melanogaster. High Sugar Diet (HSD) induction of obesity in flies has been associated with fly hyperosmolarity and glucotoxicity, while High ...
Oscar Hilary Asiimwe, John Rubaihayo, Sheu Oluwadare Sulaiman, Lawrence Obado Osuwat, Keneth Iceland Kasozi   +4 more
doaj  

Clock mutants of Drosophila melanogaster.

Proceedings of the National Academy of Sciences of the United States of America, 1971
Three mutants have been isolated in which the normal 24-hour rhythm is drastically changed. One mutant is arrhythmic; another has a period of 19 hr; a third has a period of 28 hr.
R. Konopka, S. Benzer
semanticscholar   +1 more source

An age-of-allele test of neutrality for transposable element insertions [PDF]

, 2013
How natural selection acts to limit the proliferation of transposable elements (TEs) in genomes has been of interest to evolutionary biologists for many years.
Bergman, Casey M., Blumenstiel, Justin P., Chen, Xi, He, Miaomiao   +3 more
core   +2 more sources

Bridging the Gap Between Human Toxicology and Ecotoxicology Under One Health Perspective by a Cross‐Species Adverse Outcome Pathway Network for Reproductive Toxicity

Environmental Toxicology and Chemistry, EarlyView.
Cross‐species extrapolation of adverse outcome pathway network on reproductive toxicity under the One Health perspective using new approach methodologies. AOP = adverse outcome pathway. Abstract Although ecotoxicological and toxicological risk assessments are performed separately from each other, recent efforts have been made in both disciplines to ...
Elizabeth Dufourcq Sekatcheff, Jaeseong Jeong, Jinhee Choi   +2 more
wiley   +1 more source

Renal neuroendocrine control of desiccation and cold tolerance by Drosophila suzukii [PDF]

, 2017
Background: Neuropeptides are central to the regulation of physiological, and behavioural processes in insects, directly impacting cold and desiccation survival.
Al-Anzi, Asplen, Atallah, Audsley, Cabrero, Cabrero, Cannell, Choi, Chown, Cini, Coast, Coast, Condon, Dalton, David, Davies, Denlinger, Dow, Dow, Enriquez, Gerken, Gibbs, Goodhue, Hadley, Halberg, Hoffmann, Hoffmann, Huey, Jakobs, Jakobs, Jensen, Kacar, Kahsai, Kang, Kean, Kelty, Li, Matsumura, Matzkin, McWilliam, Nässel, O'Donnell, Plantamp, Poyet, Rajpurohit, Ryan, Schiffer, Schooley, Shearer, Sinclair, Sinclair, Sinclair, Stephens, Sørensen, Taghert, Telonis-Scott, Terblanche, Terhzaz, Terhzaz, Terhzaz, Tochen, Toxopeus, Wallingford, Yeoh   +63 more
core   +2 more sources

Chromatin epigenetics and nuclear lamina keep the nucleus in shape: Examples from natural and accelerated aging

Biology of the Cell, Volume 115, Issue 1, January 2023., 2023
We review here recent studies reporting the importance of both nuclear lamina components and epigenetic modifications of chromatin in nuclear mechanics. Perturbation of chromatin condensation or nuclear lamina has been linked to a plethora of biological conditions whose most studied examples are accelerated Hutchinson‐Gilford Progeria Syndrome (HGPS ...
Pietro Salvatore Carollo, Viviana Barra
wiley   +1 more source

Infection Dynamics and Immune Response in a Newly Described Drosophila-Trypanosomatid Association

mBio, 2015
Trypanosomatid parasites are significant causes of human disease and are ubiquitous in insects. Despite the importance of Drosophila melanogaster as a model of infection and immunity and a long awareness that trypanosomatid infection is common in the ...
Phineas T. Hamilton, Jan Votýpka, Anna Dostálová, Vyacheslav Yurchenko, Nathan H. Bird, Julius Lukeš, Bruno Lemaitre, Steve J. Perlman   +7 more
doaj   +1 more source

FlyBase: introduction of the Drosophila melanogaster Release 6 reference genome assembly and large-scale migration of genome annotations

Nucleic Acids Res., 2014
Release 6, the latest reference genome assembly of the fruit fly Drosophila melanogaster, was released by the Berkeley Drosophila Genome Project in 2014; it replaces their previous Release 5 genome assembly, which had been the reference genome assembly ...
G. D. Santos, A. Schroeder, J. Goodman, V. Strelets, M. Crosby, Jim Thurmond, D. Emmert, W. Gelbart   +7 more
semanticscholar   +1 more source

Revised Annotations, Sex-Biased Expression, and Lineage-Specific Genes in the Drosophila melanogaster group

, 2014
Here, we provide revised gene models for D. ananassae, D. yakuba, and D. simulans, which include UTRs and empirically verified intron-exon boundaries, as well as ortholog groups identified using a fuzzy reciprocal-best-hit blast comparison.
Andolfatto, Peter, Rogers, Rebekah L., Sanjak, Jaleal S., Shao, Ling, Thornton, Kevin R.   +4 more
core   +1 more source

Guidelines for Studying the Oxidative Stress Damage Model on Drosophila melanogaster

Future Postharvest and Food, EarlyView.
This guideline introduced Drosophila as a research model to summarize in detail the research methods of indicators that can characterize oxidative stress. It generally includes four aspects such as generation of ROS, damage caused by ROS, antioxidant defense, and cell stress repair and apoptosis.
Quanyong Wu
wiley   +1 more source