Results 21 to 30 of about 313,024 (307)

Minibrain/Dyrk1a regulates food intake through the Sir2-FOXO-sNPF/NPY pathway in Drosophila and mammals. [PDF]

open access: yesPLoS Genetics, 2012
Feeding behavior is one of the most essential activities in animals, which is tightly regulated by neuroendocrine factors. Drosophila melanogaster short neuropeptide F (sNPF) and the mammalian functional homolog neuropeptide Y (NPY) regulate food intake.
Seung-Hyun Hong   +9 more
doaj   +1 more source

Patterns of nucleotide diversity at the regions encompassing the Drosophila insulin-like peptide (dilp) genes: demography vs. positive selection in Drosophila melanogaster. [PDF]

open access: yesPLoS ONE, 2013
In Drosophila, the insulin-signaling pathway controls some life history traits, such as fertility and lifespan, and it is considered to be the main metabolic pathway involved in establishing adult body size.
Sara Guirao-Rico, Montserrat Aguadé
doaj   +1 more source

Twenty-seven ZAD-ZNF genes of Drosophila melanogaster are orthologous to the embryo polarity determining mosquito gene cucoid.

open access: yesPLoS ONE, 2023
The C2H2 zinc finger gene cucoid establishes anterior-posterior (AP) polarity in the early embryo of culicine mosquitoes. This gene is unrelated to genes that establish embryo polarity in other fly species (Diptera), such as the homeobox gene bicoid ...
Muzi Li   +4 more
doaj   +1 more source

Pupal size as a proxy for fat content in laboratory-reared and field-collected Drosophila species

open access: yesScientific Reports, 2022
In arthropods, larger individuals tend to have more fat reserves, but data for many taxa are still missing. For the vinegar fly Drosophila melanogaster, only few studies have provided experimental data linking body size to fat content.
Thomas Enriquez   +3 more
doaj   +1 more source

Drosophila melanogaster establishes a species-specific mutualistic interaction with stable gut-colonizing bacteria

open access: yesbioRxiv, 2018
Animals live together with diverse bacteria that can impact their biology. In Drosophila melanogaster, gut-associated bacterial communities are relatively simple in composition but also have a strong impact on host development and physiology. However, it
Inês S. Pais   +3 more
semanticscholar   +1 more source

Drosophila melanogaster: A Model Organism to Study Cancer

open access: yesFrontiers in Genetics, 2019
Cancer is a multistep disease driven by the activation of specific oncogenic pathways concomitantly with the loss of function of tumor suppressor genes that act as sentinels to control physiological growth.
Z. Mirzoyan   +5 more
semanticscholar   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei   +4 more
wiley   +1 more source

Contrasting patterns of transposable element insertions in Drosophila heat-shock promoters. [PDF]

open access: yesPLoS ONE, 2009
The proximal promoter regions of heat-shock genes harbor a remarkable number of P transposable element (TE) insertions relative to both positive and negative control proximal promoter regions in natural populations of Drosophila melanogaster.
Robert A Haney, Martin E Feder
doaj   +1 more source

Comparison of Preference for Chemicals Associated with Fruit Fermentation between Drosophila melanogaster and Drosophila suzukii and between Virgin and Mated D. melanogaster

open access: yesInsects, 2023
Two taxonomically similar Drosophila species, Drosophila melanogaster and Drosophila suzukii, are known to have distinct habitats: D. melanogaster is mostly found near overripe and fermented fruits, whereas D. suzukii is attracted to fresh fruits.
Hyemin Kim   +3 more
doaj   +1 more source

Anatomy and Physiology of the Digestive Tract of Drosophila melanogaster

open access: yesGenetics, 2018
The gastrointestinal tract has recently come to the forefront of multiple research fields. It is now recognized as a major source of signals modulating food intake, insulin secretion and energy balance.
I. Miguel-Aliaga   +2 more
semanticscholar   +1 more source

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