Autophagy in Drosophila melanogaster
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2009 Macroautophagy (autophagy) is a bulk cytoplasmic degradation process that is conserved from yeast to mammals. Autophagy is an important cellular response to starvation and stress, and plays critical roles in development, cell death, aging, immunity, and cancer.
Eric H. Baehrecke, Christina K. McPhee
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Drosophila tan Encodes a Novel Hydrolase Required in Pigmentation and Vision [PDF]
, 2005 Many proteins are used repeatedly in development, but usually the function of the protein is similar in the different contexts. Here we report that the classical Drosophila melanogaster locus tan encodes a novel enzyme required for two very different ...
Bernhard T Hovemann +10 more
core +13 more sources
Patterns of nucleotide diversity at the regions encompassing the Drosophila insulin-like peptide (dilp) genes: demography vs. positive selection in Drosophila melanogaster. [PDF]
PLoS ONE, 2013 In Drosophila, the insulin-signaling pathway controls some life history traits, such as fertility and lifespan, and it is considered to be the main metabolic pathway involved in establishing adult body size.
Sara Guirao-Rico, Montserrat Aguadé
doaj +1 more source
Circadian Entrainment of Drosophila Melanogaster [PDF]
Journal of Visualized Experiments, 2020 Nearly universal among organisms, circadian rhythms coordinate biological activity to earth's orbit around the sun. To identify factors creating this rhythm and to understand the resulting outputs, entrainment of model organisms to defined circadian time-points is required.
Dayanne V Cornelio-Parra +9 more
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Divergence and introgression among the virilis group of Drosophila
Evolution Letters, Volume 6, Issue 6, Page 537-551, December 2022., 2022 Abstract Speciation with gene flow is now widely regarded as common. However, the frequency of introgression between recently diverged species and the evolutionary consequences of gene flow are still poorly understood. The virilis group of Drosophila contains 12 species that are geographically widespread and show varying levels of prezygotic and ...
Leeban H. Yusuf +3 more
wiley +1 more source
Nejire/dCBP-mediated control of H3 acetylation and transcriptional regulation by testis-specific Plus3 domain proteins during Drosophila spermatogenesis [PDF]
, 2018 Spermatogenesis describes the development from germ line stem cells to highly specialized sperm. Drosophila melanogaster spermatogenesis is a good model system for chromatin remodelling processes as many of these processes are similar in mammals and in ...
Hundertmark, Tim
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The developmental transcriptome of Drosophila melanogaster [PDF]
Nature, 2010 Drosophila melanogaster is one of the most well studied genetic model organisms; nonetheless, its genome still contains unannotated coding and non-coding genes, transcripts, exons and RNA editing sites. Full discovery and annotation are pre-requisites for understanding how the regulation of transcription, splicing and RNA editing directs the ...
Yi Zou +49 more
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Destabilization of mutated human PUS3 protein causes intellectual disability
Human Mutation, Volume 43, Issue 12, Page 2063-2078, December 2022., 2022 The homodimer of pseudouridine synthase 3 converts uridines at position 39 in tRNAs to pseudouridine (ψ), which affects tRNA stability and regulates RNA–protein interactions. Several patient‐derived variants of PUS3 have been associated with neurodegenerative diseases.
Ting‐Yu Lin +17 more
wiley +1 more source
Multifractal analysis of the long-range correlations in the cardiac dynamics of Drosophila melanogaster [PDF]
Chaos, Solitons and Fractals, vol. 28, p.p. 768-775 (2006), 2005 Time series of heartbeat activity of humans can exhibit long-range correlations. In this paper we show that such kind of correlations can exist for the heartbeat activity of much simpler species like Drosophila melanogaster. By means of the method of multifractal detrended fluctuation analysis (MFDFA) we calculate fractal spectra $f(\alpha)$ and $h(q)$
arxiv +1 more source
Pupal size as a proxy for fat content in laboratory-reared and field-collected Drosophila species
Scientific Reports, 2022 In arthropods, larger individuals tend to have more fat reserves, but data for many taxa are still missing. For the vinegar fly Drosophila melanogaster, only few studies have provided experimental data linking body size to fat content.
Thomas Enriquez +3 more
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