Results 31 to 40 of about 313,024 (307)

A genome-wide gene function prediction resource for Drosophila melanogaster. [PDF]

PLoS ONE, 2010
Predicting gene functions by integrating large-scale biological data remains a challenge for systems biology. Here we present a resource for Drosophila melanogaster gene function predictions.
Han Yan, Kavitha Venkatesan, John E Beaver, Niels Klitgord, Muhammed A Yildirim, Tong Hao, David E Hill, Michael E Cusick, Norbert Perrimon, Frederick P Roth, Marc Vidal   +10 more
doaj   +1 more source

A protein restricted diet induces a stable increased fat storage phenotype in flies

Toxicology Reports, 2023
Background: Scientific evidence has revealed possible confounders in diet induced obesity models of Drosophila melanogaster. High Sugar Diet (HSD) induction of obesity in flies has been associated with fly hyperosmolarity and glucotoxicity, while High ...
Oscar Hilary Asiimwe, John Rubaihayo, Sheu Oluwadare Sulaiman, Lawrence Obado Osuwat, Keneth Iceland Kasozi   +4 more
doaj   +1 more source

Anti-Aging Effect of Agrocybe aegerita Polysaccharide through Regulation of Oxidative Stress and Gut Microbiota

Foods, 2022
Polysaccharides extracted from Agrocybe aegerita (AAPS) have various physiological effects. In this study, we used the naturally aging Drosophila melanogaster and D-galactose-induced aging mice as animal models to study the anti-aging effects of AAPS via
Xiaoyan Liu, Linxiu Wu, Aijun Tong, Hongmin Zhen, Dong Han, Hongyang Yuan, Fannian Li, Chengtao Wang, Guangsen Fan   +8 more
doaj   +1 more source

The Drosophila melanogaster Gut Microbiota Provisions Thiamine to Its Host

mBio, 2018
The microbiota of Drosophila melanogaster has a substantial impact on host physiology and nutrition. Some effects may involve vitamin provisioning, but the relationships between microbe-derived vitamins, diet, and host health remain to be established ...
D. Sannino, A. Dobson, Katie A. Edwards, Esther R. Angert, N. Buchon   +4 more
semanticscholar   +1 more source

Rapid Evolution of Autosomal Binding Sites of the Dosage Compensation Complex in Drosophila melanogaster and Its Association With Transcription Divergence

Frontiers in Genetics, 2021
How pleiotropy influences evolution of protein sequence remains unclear. The male-specific lethal (MSL) complex in Drosophila mediates dosage compensation by 2-fold upregulation of the X chromosome in males.
Aimei Dai, Yushuai Wang, Anthony Greenberg, Zhongqi Liufu, Tian Tang   +4 more
doaj   +1 more source

Identification of novel split-GAL4 drivers for the characterization of enteroendocrine cells in the Drosophila melanogaster midgut

G3: Genes, Genomes, Genetics, 2022
The Drosophila ...
Jessica M Holsopple, Kevin R Cook, Ellen M Popodi   +2 more
doaj   +1 more source

FlyAtlas 2: a new version of the Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

Nucleic Acids Res., 2017
FlyAtlas 2 (www.flyatlas2.org) is part successor, part complement to the FlyAtlas database and web application for studying the expression of the genes of Drosophila melanogaster in different tissues of adults and larvae.
D. Leader, Sue A. Krause, Aniruddha A. Pandit, S. Davies, J. Dow   +4 more
semanticscholar   +1 more source

Triacylglycerol Metabolism in Drosophila melanogaster

Genetics, 2018
Triacylglycerol (TAG) is the most important caloric source with respect to energy homeostasis in animals. In addition to its evolutionarily conserved importance as an energy source, TAG turnover is crucial to the metabolism of structural and signaling ...
C. Heier, R. Kühnlein
semanticscholar   +1 more source

The developmental proteome of Drosophila melanogaster

Genome Research, 2017
Drosophila melanogaster is a widely used genetic model organism in developmental biology. While this model organism has been intensively studied at the RNA level, a comprehensive proteomic study covering the complete life cycle is still missing. Here, we
Nuria Casas-Vila, Alina Bluhm, Sergi Sayols, Nadja Dinges, Mario Dejung, Tina Altenhein, Dennis Kappei, B. Altenhein, Jean-Yves Roignant, F. Butter   +9 more
semanticscholar   +1 more source

Neuroprotective Effect and Mechanism of Xanthoceras sorbifolium Oil on Drosophila melanogaster with Alzheimer's Disease

Shipin gongye ke-ji
This study aimed to investigate the neuroprotective effect of Xanthoceras sorbifolium oil (XSO) on the Drosophila melanogaster model of Alzheimer's disease (AD) and to explore the underlying mechanism.
Chenyao XIANG, Duoduo REN, Xuejun CHAI, Jiayue WU, Xiaofan LIU, Yuyu ZHAO, Yongkang ZHAO, Xiaoyan ZHU, Shanting ZHAO   +8 more
doaj   +1 more source