Results 71 to 80 of about 428,367 (405)

A genome-wide gene function prediction resource for Drosophila melanogaster. [PDF]

PLoS ONE, 2010
Predicting gene functions by integrating large-scale biological data remains a challenge for systems biology. Here we present a resource for Drosophila melanogaster gene function predictions.
Han Yan, Kavitha Venkatesan, John E Beaver, Niels Klitgord, Muhammed A Yildirim, Tong Hao, David E Hill, Michael E Cusick, Norbert Perrimon, Frederick P Roth, Marc Vidal   +10 more
doaj   +1 more source

The number of genes in Drosophila melanogaster [PDF]

Nature, 1978
THE number of genes in an organism is one of its fundamental biological parameters and relates to the number of functions required to construct that organism and determine its physiological characteristics. It is generally assumed that with increasing organic complexity the number of genes of the species must increase.
García-Bellido, Antonio, Ripoll, Pedro
openaire   +4 more sources

Identification of novel split-GAL4 drivers for the characterization of enteroendocrine cells in the Drosophila melanogaster midgut

G3: Genes, Genomes, Genetics, 2022
The Drosophila ...
Jessica M Holsopple, Kevin R Cook, Ellen M Popodi   +2 more
doaj   +1 more source

Comprehensive overview and assessment of miRNA target prediction tools in human and drosophila melanogaster [PDF]

Current Bioinformatics (2019), 14(5): 432-445, 2017
MicroRNAs (miRNAs) are small non-coding RNAs that control gene expression at the post-transcriptional level through complementary base pairing with the target mRNA, leading to mRNA degradation and blocking translation process. Any dysfunctions of these small regulatory molecules have been linked with the development and progression of several diseases.
arxiv   +1 more source

The Drosophila melanogaster Genetic Reference Panel

Nature, 2012
A major challenge of biology is understanding the relationship between molecular genetic variation and variation in quantitative traits, including fitness.
T. Mackay, S. Richards, Eric A. Stone, A. Barbadilla, J. Ayroles, Dianhui Zhu, Sònia Casillas, Yi Han, M. Magwire, J. Cridland, M. Richardson, R. Anholt, Maite G. Barrón, Crystal Bess, K. Blankenburg, M. A. Carbone, David Castellano, Lesley S. Chaboub, Laura H. Duncan, Zeke Harris, Mehwish Javaid, J. Jayaseelan, S. Jhangiani, K. Jordan, F. Lara, Faye Lawrence, Sandy Lee, P. Librado, Raquel Linheiro, R. F. Lyman, A. Mackey, Mala Munidasa, D. Muzny, L. Nazareth, I. Newsham, Lora Perales, ling-ling Pu, Carson Qu, Miquel Ràmia, J. Reid, S. Rollmann, J. Rozas, Nehad I. Saada, Lavanya Turlapati, K. Worley, Yuanqing Wu, A. Yamamoto, Yiming Zhu, C. Bergman, Kevin R. Thornton, D. Mittelman, R. Gibbs   +51 more
semanticscholar   +1 more source

Functional relevance of the newly evolved sperm dynein intermediate chain multigene family in Drosophila melanogaster males. [PDF]

, 2012
In many animal species, traits associated with male fitness evolve rapidly. Intersexual conflict and male-male competition have been suggested to drive this rapid evolution.
Abbassi, Mashya, Do, Tiffanie, Ranz, José M, Yeh, Shu-Dan   +3 more
core   +2 more sources

Rapid Evolution of Autosomal Binding Sites of the Dosage Compensation Complex in Drosophila melanogaster and Its Association With Transcription Divergence

Frontiers in Genetics, 2021
How pleiotropy influences evolution of protein sequence remains unclear. The male-specific lethal (MSL) complex in Drosophila mediates dosage compensation by 2-fold upregulation of the X chromosome in males.
Aimei Dai, Yushuai Wang, Anthony Greenberg, Zhongqi Liufu, Tian Tang   +4 more
doaj   +1 more source

FlyAtlas 2: a new version of the Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

Nucleic Acids Res., 2017
FlyAtlas 2 (www.flyatlas2.org) is part successor, part complement to the FlyAtlas database and web application for studying the expression of the genes of Drosophila melanogaster in different tissues of adults and larvae.
D. Leader, Sue A. Krause, Aniruddha A. Pandit, S. Davies, J. Dow   +4 more
semanticscholar   +1 more source

The translation factors ofDrosophila melanogaster [PDF]

Fly, 2016
Synthesis of polypeptides from mRNA (translation) is a fundamental cellular process that is coordinated and catalyzed by a set of canonical 'translation factors'. Surprisingly, the translation factors of Drosophila melanogaster have not yet been systematically identified, leading to inconsistencies in their nomenclature and shortcomings in functional ...
Marygold, Steven J, Attrill, Helen, Lasko, Paul   +2 more
openaire   +5 more sources

Circadian Rhythms and Sleep in Drosophila melanogaster

Genetics, 2017
The advantages of the model organism Drosophila melanogaster, including low genetic redundancy, functional simplicity, and the ability to conduct large-scale genetic screens, have been essential for understanding the molecular nature of circadian (∼24 hr)
Christine Dubowy, A. Sehgal
semanticscholar   +1 more source