Results 61 to 70 of about 49,670 (247)

Impact of Corn Meal and Wild Yeast Media on Drosophila Diversity in the Assam-Meghalaya Rolling Terrain [PDF]

نامه انجمن حشره‌شناسی ایران
The distribution and diversity of Drosophila species across six sites in the rolling terrain between Assam and Meghalaya, employing trap-bait and net sweeping methods throughout the year.
Aparajita Rabha, Dhirendra K Sharma, Chittaranjan Baruah, Arup Nama Das   +3 more
doaj   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Investigating Mitochondrial Gene Expression Patterns in Drosophila melanogaster Using Network Analysis to Understand Aging Mechanisms

Applied Sciences, 2023
The process of aging is a complex phenomenon that involves a progressive decline in physiological functions required for survival and fertility. To better understand the mechanisms underlying this process, the scientific community has utilized several ...
Manuel Mangoni, Francesco Petrizzelli, Niccolò Liorni, Salvatore Daniele Bianco, Tommaso Biagini, Alessandro Napoli, Marta Adinolfi, Pietro Hiram Guzzi, Antonio Novelli, Viviana Caputo, Tommaso Mazza   +10 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A comparative study of the short term cold resistance response in distantly related Drosophila species: the role of regucalcin and frost. [PDF]

PLoS ONE, 2011
The molecular basis of short term cold resistance (indexed as chill-coma recovery time) has been mostly addressed in D. melanogaster, where candidate genes (Dca (also known as smp-30) and Frost (Fst)) have been identified.
Micael Reis, Cristina P Vieira, Ramiro Morales-Hojas, Bruno Aguiar, Hélder Rocha, Christian Schlötterer, Jorge Vieira   +6 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Antistress property of Glycyrrhiza glabra (Athimadhura) on stress induced Drosophila melanogaster [PDF]

Journal of Stress Physiology & Biochemistry, 2010
Stress is defined as a condition that disturbs the normal function of the biological system or a condition that decreases fitness. The present study was to evaluate the antistress property of Glycyrrhiza glabra (Athimadura).
Sowmya M., Sathish Kumar B.Y.
doaj  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

The behavior of sympatric Chilean populations of Drosophila larvae during pupation

Genetics and Molecular Biology, 1998
The behavioral mechanisms by which the larvae of sympatric Chilean populations of Drosophila melanogaster, D. simulans, D. hydei and D. busckii select pupation sites are described in terms of larval substrate preferences.
Raúl Godoy-Herrera, José Luis Silva-Cuadra   +1 more
doaj   +1 more source