Results 61 to 70 of about 280,859 (262)

Asymmetric Evolution of Antennal Cell Types Underlies a Derived Ammonia‐Sensing Logic for Ecological Adaptation in Bactrocera dorsalis

Advanced Science, EarlyView.
Comparative antennal single‐nucleus transcriptomics reveals cell‐type‐dependent transcriptomic divergence in Bactrocera dorsalis, with similar structural cells but divergent sensory neurons. This neuronal diversification is associated with a distinct ammonia‐sensing pathway, linking female attraction to bird‐dropping‐associated cues with nutritional ...
Wei Liu, Shuai Zhang, Jie Zhang, Zhen Tian, Yuanbo Xue, Ling Yang, Jun Xu, Guirong Wang   +7 more
wiley   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Impact of Corn Meal and Wild Yeast Media on Drosophila Diversity in the Assam-Meghalaya Rolling Terrain [PDF]

نامه انجمن حشره‌شناسی ایران
The distribution and diversity of Drosophila species across six sites in the rolling terrain between Assam and Meghalaya, employing trap-bait and net sweeping methods throughout the year.
Aparajita Rabha, Dhirendra K Sharma, Chittaranjan Baruah, Arup Nama Das   +3 more
doaj   +1 more source

Recurrent Neurodevelopmental Disorder Associated With a Dominant‐Negative TOP2B H63Y Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We describe a 7 year‐old boy with severe neurodevelopmental disorder, medically‐refractory epileptic encephalopathy, hyperkinetic movement disorder, hypotonia, cerebral and cerebellar atrophy and hypomyelination who was found to have a heterozygous de novo TOP2B NM_001330700.2:c.187C>T, p.(His63Tyr) variant.
Zong Yi Ha, Leticia Dinatto, Kirsten Meagher, Colleen Guimond, Jan M. Friedman, Peter C. Stirling, Millan S. Patel   +6 more
wiley   +1 more source

Patterns of intron sequence evolution in Drosophila are dependent upon length and GC content [PDF]

, 2005
Introns comprise a large fraction of eukaryotic genomes, yet little is known about their functional significance. Regulatory elements have been mapped to some introns, though these are believed to account for only a small fraction of genome wide intronic
Haddrill, Penelope R, Halligan, D L, Charlesworth, B, Daniel L Halligan, Haddrill, P R, Peter Andolfatto, Charlesworth, Brian, Brian Charlesworth, Halligan, Daniel L, Penelope R Haddrill, Andolfatto, Peter, Andolfatto, P   +11 more
core   +3 more sources

Quantification of food intake in Drosophila [PDF]

, 2009
Measurement of food intake in the fruit fly Drosophila melanogaster is often necessary for studies of behaviour, nutrition and drug administration. There is no reliable and agreed method for measuring food intake of flies in undisturbed, steady state ...
Linda Partridge, Partridge, L., Wong, Richard, Matthew D. W. Piper, Partridge Linda, Richard Wong, Wong, R., Wertheim, B., Wertheim, B, Matthew D W Piper, Piper, Matthew D W, Piper, M.D.W., Partridge, Linda, Wertheim Bregje, Wong, R, Piper, MDW, Wertheim, Bregje, Piper Matthew D. W., Wertheim, Bregje; id_orcid, Partridge, L, Bregje Wertheim, Piper, M., Raine, N.E., Wong Richard   +23 more
core   +2 more sources

Antistress property of Glycyrrhiza glabra (Athimadhura) on stress induced Drosophila melanogaster [PDF]

Journal of Stress Physiology & Biochemistry, 2010
Stress is defined as a condition that disturbs the normal function of the biological system or a condition that decreases fitness. The present study was to evaluate the antistress property of Glycyrrhiza glabra (Athimadura).
Sowmya M., Sathish Kumar B.Y.
doaj  

Experimental Control and Characterization of Autophagy in Drosophila [PDF]

, 2008
Insects such as the fruit fly Drosophila melanogaster, which fundamentally reorganize their body plan during metamorphosis, make extensive use of autophagy for their normal development and physiology.
Thomas P. Neufeld, Neufeld, Thomas P., Gabor Juhasz, Juhász, Gábor   +3 more
core   +1 more source

A comparative study of the short term cold resistance response in distantly related Drosophila species: the role of regucalcin and frost. [PDF]

PLoS ONE, 2011
The molecular basis of short term cold resistance (indexed as chill-coma recovery time) has been mostly addressed in D. melanogaster, where candidate genes (Dca (also known as smp-30) and Frost (Fst)) have been identified.
Micael Reis, Cristina P Vieira, Ramiro Morales-Hojas, Bruno Aguiar, Hélder Rocha, Christian Schlötterer, Jorge Vieira   +6 more
doaj   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

Arthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento da Conceicao, Neelanjan Vishnu, Shankara N. Varadarajan, Venugopal R. Bovilla, Rajender K. Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source