Results 71 to 80 of about 437,033 (326)

Organization of descending neurons in Drosophila melanogaster

Scientific Reports, 2016
Neural processing in the brain controls behavior through descending neurons (DNs) - neurons which carry signals from the brain to the spinal cord (or thoracic ganglia in insects).
Cynthia T. Hsu, Vikas Bhandawat
semanticscholar   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

A comparative study of the short term cold resistance response in distantly related Drosophila species: the role of regucalcin and frost. [PDF]

PLoS ONE, 2011
The molecular basis of short term cold resistance (indexed as chill-coma recovery time) has been mostly addressed in D. melanogaster, where candidate genes (Dca (also known as smp-30) and Frost (Fst)) have been identified.
Micael Reis, Cristina P Vieira, Ramiro Morales-Hojas, Bruno Aguiar, Hélder Rocha, Christian Schlötterer, Jorge Vieira   +6 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Investigating Mitochondrial Gene Expression Patterns in Drosophila melanogaster Using Network Analysis to Understand Aging Mechanisms

Applied Sciences, 2023
The process of aging is a complex phenomenon that involves a progressive decline in physiological functions required for survival and fertility. To better understand the mechanisms underlying this process, the scientific community has utilized several ...
Manuel Mangoni, Francesco Petrizzelli, Niccolò Liorni, Salvatore Daniele Bianco, Tommaso Biagini, Alessandro Napoli, Marta Adinolfi, Pietro Hiram Guzzi, Antonio Novelli, Viviana Caputo, Tommaso Mazza   +10 more
doaj   +1 more source

Graded requirement for the zygotic terminal gene, tailless, in the brain and tail region of the Drosophila embryo [PDF]

, 1988
We have used hypomorphic and null tailless (tll) alleles to carry out a detailed analysis of the effects of the lack of tll gene activity on anterior and posterior regions of the embryo.
Lengyel, Judith A., Merriam, John R., Strecker, Teresa R.   +2 more
core  

Genome of Drosophila suzukii, the spotted wing drosophila. [PDF]

, 2013
Drosophila suzukii Matsumura (spotted wing drosophila) has recently become a serious pest of a wide variety of fruit crops in the United States as well as in Europe, leading to substantial yearly crop losses.
Begun, David J, Chiu, Joanna C, Cridland, Julie M, Hamby, Kelly A, Hamm, Christopher A, Jiang, Xuanting, Kwok, Rosanna S, Lee, Ernest K, Saelao, Perot, Walton, Vaughn M, Zalom, Frank G, Zhang, Guojie, Zhao, Li   +12 more
core   +2 more sources

A connectome and analysis of the adult Drosophila central brain

bioRxiv, 2020
The neural circuits responsible for animal behavior remain largely unknown. We summarize new methods and present the circuitry of a large fraction of the brain of the fruit fly Drosophila melanogaster.
Louis K. Scheffer, C. Xu, M. Januszewski, Zhiyuan Lu, Zhiyuan Lu, Shin-ya Takemura, K. Hayworth, Gary B. Huang, Kazunori Shinomiya, Jeremy Maitlin-Shepard, S. Berg, Jody Clements, Philip M. Hubbard, W. Katz, L. Umayam, Ting Zhao, David Ackerman, T. Blakely, J. Bogovic, Tom Dolafi, Dagmar Kainmueller, Takashi Kawase, K. Khairy, Laramie Leavitt, Peter H. Li, Larry F. Lindsey, Nicole L. Neubarth, D. J. Olbris, H. Otsuna, Eric T. Trautman, Masayoshi Ito, Masayoshi Ito, A. S. Bates, Jens Goldammer, Jens Goldammer, T. Wolff, Rob Svirskas, P. Schlegel, Erika Neace, Christopher Knecht, Chelsea X. Alvarado, Dennis Bailey, Samantha Ballinger, J. Borycz, Brandon S Canino, Natasha Cheatham, Michael Cook, M. Dreher, O. Duclos, Bryon Eubanks, K. Fairbanks, Samantha Finley, N. Forknall, Audrey Francis, G. Hopkins, Emily M Joyce, SungJin Kim, Nicole A Kirk, Julie Kovalyak, Shirley A Lauchie, Alanna Lohff, Charli A Maldonado, Emily A Manley, Sari McLin, Caroline Mooney, Miatta Ndama, Omotara Ogundeyi, Nneoma Okeoma, Christopher Ordish, Nicholas Padilla, Christopher Patrick, Tyler Paterson, Elliott Phillips, E. M. Phillips, Neha Rampally, C. Ribeiro, Madelaine K Robertson, J. Rymer, S. Ryan, Megan Sammons, A. K. Scott, Ashley L. Scott, A. Shinomiya, Claire Smith, Kelsey Smith, Natalie Smith, Margaret A. Sobeski, A. Suleiman, Jackie Swift, Satoko Takemura, Iris Talebi, Dorota Tarnogorska, Emily Tenshaw, Temour Tokhi, J. Walsh, Tansy Yang, J. Horne, Feng Li, Ruchi Parekh, P. Rivlin, V. Jayaraman, Marta Costa, G. Jefferis, G. Jefferis, Kei Ito, Kei Ito, Kei Ito, S. Saalfeld, R. George, I. Meinertzhagen, I. Meinertzhagen, G. Rubin, H. Hess, Viren Jain, Stephen M. Plaza   +114 more
semanticscholar   +1 more source

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

Advanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo, Mengda Ren, Gavin Wen Zhao Loi, Eka Norfaishanty Saipuljumri, Jonathan Indajang, Kah Leong Lim, Jialiu Zeng   +6 more
wiley   +1 more source

Antistress property of Glycyrrhiza glabra (Athimadhura) on stress induced Drosophila melanogaster [PDF]

Journal of Stress Physiology & Biochemistry, 2010
Stress is defined as a condition that disturbs the normal function of the biological system or a condition that decreases fitness. The present study was to evaluate the antistress property of Glycyrrhiza glabra (Athimadura).
Sowmya M., Sathish Kumar B.Y.
doaj