Results 111 to 120 of about 5,995,584 (403)
A cell-specific enhancer that specifies lin-3 expression in the C. elegans anchor cell for vulval development [PDF]
, 2004 During C. elegans vulval development, the anchor cell (AC) in the somatic gonad expresses lin-3, activating the EGF receptor signaling pathway in vulval precursor cells (VPCs) and thereby inducing and patterning VPCs.
Hwang, Byung Joon, Sternberg, Paul W.
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Histone Demethylase UTX Suppresses Tumor Cell Proliferation by Regulating Stress Granules
Advanced Science, EarlyView.These findings indicate that cytoplasmic UTX forms puncta and co‐localizes in stress granules (SGs) upon various stresses. UTX TPR‐domain‐dependently and demethylase‐activity‐independently destabilize SGs by binding G3BP1, the SG hub protein, to disrupt SG network, thus affects tumorigenesis.
Xikai Liu +17 more
wiley +1 more source
Regulation of Synaptic Pumilio Function by an Aggregation-Prone Domain [PDF]
, 2010 We identified Pumilio (Pum), a Drosophila translational repressor, in a computational search for metazoan proteins whose activities might be regulated by assembly into ordered aggregates.
Menon, Kaushiki P. +3 more
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O-GlcNAcase contributes to cognitive function in Drosophila [PDF]
, 2020 Contains fulltext : 219183.pdf (publisher's version ) (Open ...
Catinozzi, Marica +7 more
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Proceedings of the National Academy of Sciences of the United States of America, 1982 The primary base sequence of the protein coding regions of the four small heat shock genes of Drosophila melanogaster present at cytological locus 67B has been determined.
T. D. Ingolia, E. Craig
semanticscholar +1 more source
Purification of Drosophila Acidic Ribosomal Proteins [PDF]
European Journal of Biochemistry, 1982 The relatively acidic proteins (group A80) of Drosophila melanogaster ribosomes were separated by ion-exchange chromatography. Fractions containing one or more acidic proteins were combined into thirteen pools. The criterion for the combination was the migration pattern in one-dimensional polyacrylamide gels containing sodium dodecyl sulphate.
W. Yean Chooi +6 more
openaire +3 more sources
Advanced Science, EarlyView.This study demonstrates that mutant FAT1 promotes ASCL2‐driven, CPT1A‐dependent fatty acid oxidation, leading to resistance to CPI‐613‐mediated TCA cycle inhibition in head and neck cancer. In vivo gene depletion of mutant FAT1 with LNP‐sgFAT1 suppresses tumor growth and restores CPI‐613 sensitivity, revealing a targetable metabolic bypass with ...
Fanghui Chen +11 more
wiley +1 more source
Label-free quantitative proteomic analysis of adult Drosophila heads
STAR Protocols, 2022 Summary: LIR motif-containing proteins (LIRCPs) bind to LDS (LIR motif docking site) of Atg8-family proteins. In this protocol, we describe steps to identify Drosophila LIRCPs, in Atg8a LDS mutants we have created, via label-free quantitative proteomic ...
Yan Zhang, Ioannis P. Nezis
doaj
TRP and Rhodopsin Transport Depends on Dual XPORT ER Chaperones Encoded by an Operon
Cell Reports, 2015 TRP channels and G protein-coupled receptors (GPCRs) play critical roles in sensory reception. However, the identities of the chaperones that assist GPCRs in translocating from the endoplasmic reticulum (ER) are limited, and TRP ER chaperones are ...
Zijing Chen +2 more
doaj +1 more source
Tre1 GPCR initiates germ cell transepithelial migration by regulating Drosophila melanogaster E-cadherin [PDF]
, 2008 Despite significant progress in identifying the guidance pathways that control cell migration, how a cell starts to move within an intact organism, acquires motility, and loses contact with its neighbors is poorly understood.
Barbosa, Vitor +5 more
core +3 more sources