Results 121 to 130 of about 5,958,148 (313)

Identification of Two Proteins Required for Conjunction and Regular Segregation of Achiasmate Homologs in Drosophila Male Meiosis [PDF]

, 2005
Sharon E. Thomas, Morvarid Soltani‐Bejnood, Peggy Roth, Rainer Dorn, John M. Logsdon, Bruce D. McKee   +5 more
openalex   +1 more source

Polyphenol diet and exercise as neuroprotective factors in a Drosophila model of Alzheimer's disease

Animal Models and Experimental Medicine, EarlyView.
Moderate exercise and low‐dose ellagic acid supplementation improved motor performance, learning, and longevity in a transgenic Drosophila model of Alzheimer's disease. Both interventions showed hormetic effects—that is, beneficial at low levels, but detrimental at higher intensities or doses.
Michelle Morgan, Zaida Lopez Rodriguez, Richard E. Hartman   +2 more
wiley   +1 more source

Protein Kinase D regulates several aspects of development in Drosophila melanogaster [PDF]

, 2007
Dieter Maier, Anja C. Nagel, Gloc Helena, Angelika Haußer, Sabrina J. Kugler, Irmgard Wech, Anette Preiss   +6 more
openalex   +1 more source

C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins

Science, 2014
S. Mizielinska, Sebastian Grönke, T. Niccoli, Charlotte E. Ridler, E. Clayton, A. Devoy, T. Moens, F. Norona, I. Woollacott, J. Pietrzyk, K. Cleverley, Andrew J. Nicoll, S. Pickering-Brown, Jacqueline Dols, M. Cabecinha, Oliver Hendrich, P. Fratta, E. Fisher, L. Partridge, A. Isaacs   +19 more
semanticscholar   +1 more source

Multimorbidity and animal models

Animal Models and Experimental Medicine, EarlyView.
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang, Yakun Ren, Xingjiu Yang, Mengyuan Li, Junxiu Liu, Xiaoyan Du, Wen Wang, Ran Gao   +7 more
wiley   +1 more source

Cytoplasmic to nuclear localization of fatty-acid binding protein correlates with specific forms of long-term memory inDrosophila [PDF]

, 2011
Jason R. Gerstner, William M. Vanderheyden, Paul J. Shaw, Charles F. Landry, Jerry C. P. Yin   +4 more
openalex   +1 more source

Temporally regulated nuclear entry of the Drosophila period protein contributes to the circadian clock

, 1995
Kathryn D. Curtin, Z. Josh Huang, Michael Rosbash   +2 more
openalex   +1 more source

Non‐Synaptic Function and Localization of Syntaxin‐Binding Protein 1 in a Mouse Model of STXBP1‐Related Epileptic Encephalopathy

Annals of Neurology, EarlyView.
Objective De novo mutations in the syntaxin‐binding protein 1 (STXBP1), encoded by STXBP1, are among the most prevalent causes of variable neurodevelopmental disorders, including epileptic encephalopathy, developmental delay, and movement disorders.
Tao Yang, Rajat Banerjee, Yamei Deng, Sheetal Jahagirdar1, Alexey I. Nesvizhskii, Michael D. Uhler, Jack M. Parent, Yu Wang   +7 more
wiley   +1 more source

cGMP-Dependent Protein Kinase Encoded byforagingRegulates Motor Axon Guidance inDrosophilaby Suppressing Lola Function

, 2016
Qionglin Peng, Yijin Wang, Meixia Li, Deliang Yuan, Mengbo Xu, Changqing Li, Zhefeng Gong, Renjie Jiao, Li Liu   +8 more
openalex   +2 more sources

Hydroxycarboxylic Acid Receptor 2 Mediates β‐hydroxybutyrate's Antiseizure Effect in Mice

Annals of Neurology, EarlyView.
A Objective The ketogenic diet, a high‐fat, low‐carbohydrate regimen, is often used to treat drug‐resistant seizures and is being studied for Alzheimer's disease and other neuropsychiatric disorders. However, its mechanism of action remains unclear. β‐hydroxybutyrate, a primary circulating ketone body produced by the ketogenic diet, may mediate its ...
Soudabeh Naderi, John Williamson, Huayu Sun, Suchitra Joshi, Rachel Jane Spera, Savaira Zaib, Supriya Sharma, Chengsan Sun, Andrey Brodovskiy, Ifrah Zawar, Jaideep Kapur   +10 more
wiley   +1 more source