CrisprBuildr: an open-source application for CRISPR-mediated genome engineering in Drosophila melanogaster. [PDF]
Horsley N +4 more
europepmc +1 more source
Expression in mammalian cell cultures reveals interdependent, but distinct, functions for Star and Rhomboid proteins in the processing of the Drosophila transforming-growth-factor-α homologue Spitz [PDF]
John C. Pascall +2 more
openalex +1 more source
Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology
Abstract Maternal effects, encompassing both genetic (maternally expressed gene products) and non‐genetic (maternal state) influences, are powerful determinants of offspring phenotype, yet their RNA‐level mechanisms remain incompletely resolved. In parallel, epitranscriptomics, an emerging field centered on chemical modifications to RNA, has revealed ...
Ehsan Pashay Ahi
wiley +1 more source
The histone modification regulator, SIN3, plays a role in the cellular response to changes in glycolytic flux. [PDF]
Soukar I +5 more
europepmc +1 more source
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
Heat-shock proteins of Drosophila are associated with nuclease-resistant, high-salt-resistant nuclear structures. [PDF]
Louis Levinger, A Varshavsky
openalex +1 more source
Cross‐species extrapolation of adverse outcome pathway network on reproductive toxicity under the One Health perspective using new approach methodologies. AOP = adverse outcome pathway. Abstract Although ecotoxicological and toxicological risk assessments are performed separately from each other, recent efforts have been made in both disciplines to ...
Elizabeth Dufourcq Sekatcheff +2 more
wiley +1 more source
Deciphering the Impact of AKT1 Pathogenic Variants in Juvenile Granulosa Cell Tumors Using a Drosophila Model. [PDF]
Veitia RA +5 more
europepmc +1 more source
Sequential cleavage of the proteins encoded by HNOT/ALG3, the human counterpart of the Drosophila NOT and yeast ALG3 gene, results in products acting in distinct cellular compartments [PDF]
Benedikt Hacker +2 more
openalex +1 more source

