An Inventory of Peroxisomal Proteins and Pathways in Drosophila melanogaster
J. Faust+3 more
semanticscholar +1 more source
Investigating the role of SARM1 in central nervous system
Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1) is a pivotal molecule that has garnered extensive attention in neuroscience. As an intracellular molecule, SARM1 possesses various crucial biological functions in the nervous system.
Junjie Wang+4 more
wiley +1 more source
Protein D1 preferentially binds A + T-rich DNA in vitro and is a component of Drosophila melanogaster nucleosomes containing A + T-rich satellite DNA. [PDF]
Louis Levinger, Alexander Varshavsky
openalex +1 more source
Polycomb and Trithorax Group Genes in Drosophila
J. Kassis, J. Kennison, J. Tamkun
semanticscholar +1 more source
A hitchhiker's guide to single‐cell epigenomics: Methods and applications for cancer research
Abstract Genetic mutations are well known to influence tumorigenesis, tumor progression, treatment response and relapse, but the role of epigenetic variation in cancer progression is still largely unexplored. The lack of epigenetic understanding in cancer evolution is in part due to the limited availability of methods to examine such a heterogeneous ...
Marta Moreno‐Gonzalez+2 more
wiley +1 more source
Expression, function, and regulation of the hairy segmentation protein in the Drosophila embryo. [PDF]
Sean B. Carroll+2 more
openalex +1 more source
Enhancer‐dependent gene regulation in space, time, and malignancies
Abstract Control of cell‐type‐specific gene activation requires the coordinated activity of distal regulatory elements, including enhancers, whose inputs must be temporally integrated. Dysregulation of this regulatory capacity, such as aberrant usage of enhancers, can result in malignant transformation of cells.
Belinda Blum+2 more
wiley +1 more source
Two Drosophila melanogaster proteins related to intermediate filament proteins of vertebrate cells. [PDF]
Falko-Günter Falkner+2 more
openalex +1 more source
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner+7 more
wiley +1 more source