Results 221 to 230 of about 219,755 (269)

Adaptive protein evolution in Drosophila

Nature, 2002
For over 30 years a central question in molecular evolution has been whether natural selection plays a substantial role in evolution at the DNA sequence level. Evidence has accumulated over the last decade that adaptive evolution does occur at the protein level, but it has remained unclear how prevalent adaptive evolution is.
Nick G C, Smith, Adam, Eyre-Walker
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Protein and enzyme variation in Drosophila

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1971
Abstract 1. 1. The isoenzyme patterns of alcohol dehydrogenase (ADH), glutamate dehydrogenase (GDH), and lactate dehydrogenase (LDH), and the protein banding patterns of Drosophila affinis, D. hydei, D. melanogaster, D. simulans Amherst, D. simulans Georgetown, and D.
P W, Pappas, G E, Rodrick, J R, Diebolt
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Synthesis of drosophila X virus proteins in cultured Drosophila cells

Virology, 1984
The genome of Drosophila X virus (DXV) is made up of two segments of dsRNA with molecular weights of 2.3 X 10(6) (A) and 2.2 X 10(6) (B). Agarose gel electrophoresis of RNA fragments produced by S1 nuclease digestion of partially denatured, purified segment A and B indicated that the two genome segments have different nucleotide sequences.
E, Nagy, P, Dobos
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Drosophila Krüppel protein is a transcriptional represser

Nature, 1990
Krüppel (Kr), one of the zygotically active Drosophila segmentation genes, is expressed in a restricted domain during the blastoderm stage of embryogenesis and is involved in the control of development of the thoracic and abdominal segments of the fly.
J D, Licht, M J, Grossel, J, Figge, U M, Hansen   +3 more
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Drosophila RNA Binding Proteins

2006
RNA binding proteins are fundamental mediators of gene expression. The use of the model organism Drosophila has helped to elucidate both tissue-specific and ubiquitous functions of RNA binding proteins. These proteins mediate all aspects of the mRNA lifespan including splicing, nucleocytoplasmic transport, localization, stability, translation, and ...
Chiara, Gamberi, Oona, Johnstone, Paul, Lasko   +2 more
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Functions of piRNAs and the Piwi protein in Drosophila

Russian Journal of Genetics, 2015
Short (25-35 nucleotides) regulatory piPHK, along with RNA-binding proteins of the Piwi family, constitute an evolutionarily conserved system that functions mainly in eukaryotic gonads. The system can be regarded as a variant of the mechanism of RNA interference, which is based on the recognition of target RNA as a result of complementary interactions ...
V A, Gvozdev, A D, Stolyarenko, M S, Klenov   +2 more
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Drosophila protein tyrosine phosphatases

Seminars in Cell Biology, 1993
Seven protein tyrosine phosphatase (PTPase) genes have been identified in the fruit-fly Drosophila melanogaster. Four of these genes encode receptor-linked PTPases (R-PTPs) that are expressed on central nervous system axons in the embryo. Each axonal R-PTP has an extracellular domain that is homologous to vertebrate adhesion molecules and to identified
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Chromosomal proteins in the spermatogenesis of Drosophila

Chromosoma, 2003
Chromatin constitution in the male germ line of Drosophila is discussed with respect to the substitution of somatic histones by protamines or other basic proteins. The specific properties of germ line chromatin include the initiation and completion of the spermatogenic pathway and the reprogramming of the genome for embryonic development.
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Protein Expression in Drosophila Schneider Cells

Analytical Biochemistry, 2000
We expressed recombinant secreted, membrane, and cytosolic proteins in stably transfected Drosophila Schneider (SL-3) cells. To allow easy cloning of N- and C-terminal fusion proteins containing epitope- and His-tags for the detection of recombinant proteins and purification by affinity chromatography we constructed new expression vectors. To exemplify
J, Benting, S, Lecat, D, Zacchetti, K, Simons   +3 more
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Corepressor Proteins in Drosophila Development

2001
This review focuses on transcriptional corepressors in the early embryo of the fruit fly Drosophila melanogaster, but also considers their roles in other developmental contexts, as well as related proteins in other organisms.
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