Results 231 to 240 of about 387,028 (358)

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos   +8 more
wiley   +1 more source

Motor Protein Disruption Critically Alters Organelle Trafficking and Excitation-Contraction Coupling. [PDF]

open access: yeseNeuro
Bansal H   +5 more
europepmc   +1 more source

A mutant O-GlcNAcase as a probe to reveal global dynamics of protein O-GlcNAcylation during Drosophila embryonic development

open access: green, 2015
Daniel Mariappa   +7 more
openalex   +2 more sources

ParaHox Genes Revisited: From Gut Patterning to Integrated Axial and Neural Organization in Rotifera

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In rotifers, ParaHox genes show a dispersed genomic organization, with Xlox absent across gnathiferans. Exclusive neuronal expression of Gsx and Cdx reveals that ancestral ParaHox genes coordinated neural and epithelial development beyond gut patterning, suggesting an integrated role in early bilaterian body plan organization.
Andreas C. Fröbius   +2 more
wiley   +1 more source

Human FUS is toxic via association with RNA polymerase II in Drosophila. [PDF]

open access: yesCell Death Dis
Moens TG   +7 more
europepmc   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur   +6 more
wiley   +1 more source

Drosophila melanogaster miPEP8 Regulates Cell Size Through its Interaction With ref(2)P/p62. [PDF]

open access: yesMol Cell Proteomics
Duboé C   +12 more
europepmc   +1 more source

Innate immunity shapes the persistent transmission of plant viruses by insect vectors

open access: yesNew Plant Protection, EarlyView.
In this review, we focus on two key aspects of the virus–vector interplay: (1) persistently transmitted viruses utilize host factors to overcome transmission barriers; and (2) molecular recognition activates antiviral immunity and subsequent viral counter‐defense. Understanding these interactions offers critical insights for developing novel strategies
Gang Lu, Chuanxi Zhang, Junmin Li
wiley   +1 more source

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