Identification of locally activated spindle-associated proteins in oocytes uncovers a phosphatase-driven mechanism. [PDF]
Wan X +5 more
europepmc +1 more source
Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley +1 more source
A recurrent adaptive mutation in the transmembrane 2B protein of an insect picorna-like virus in a nonnative host. [PDF]
Lezcano OM +7 more
europepmc +1 more source
The COG database: new developments in phylogenetic classification of proteins from complete genomes
R. Tatusov +9 more
semanticscholar +1 more source
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos +8 more
wiley +1 more source
The C-terminal ZZ domain of the Drosophila ORB2 RNA-binding protein is required for spermatid individualization. [PDF]
Low TCH, Falk BL, Brill JA, Lipshitz HD.
europepmc +1 more source
Thirty-One Flavors of Drosophila Rab Proteins
Jun Zhang +9 more
semanticscholar +1 more source
Escaping Constraints to Innovate: Maternal Neofunctionalization in a HoxB4 Duplicate
Whole‐genome duplication in Xenopus laevis generated duplicated Hox genes that are largely constrained in sequence and developmental expression. However, HoxB4L uniquely acquired maternal expression through cis‐regulatory and protein structural divergence, illustrating how gene duplication enables transcription factors to escape pleiotropic constraints
Júlia de Lima Carvalho +2 more
wiley +1 more source
dFlpTag, a RMCE-based tool for simultaneous endogenous protein tagging and cell labeling in Drosophila. [PDF]
Li L +6 more
europepmc +1 more source

