Results 81 to 90 of about 5,995,584 (403)

A genome-wide resource for the analysis of protein localisation in Drosophila

open access: yesbioRxiv, 2015
The Drosophila genome contains >13,000 protein coding genes, the majority of which remain poorly investigated. Important reasons include the lack of antibodies or reporter constructs to visualise these proteins.
M. Sarov   +25 more
semanticscholar   +1 more source

Polarity proteins duel in Drosophila [PDF]

open access: yesJournal of Cell Biology, 2014
![Figure][1] A control fly embryo (left) shows a normal cuticle, whereas the cuticle has fragmented in an embryo with a nonphosphorylatable version of Yurt (right). Gamblin et al. reveal how two proteins grapple to control polarity in epithelial cells.
openaire   +2 more sources

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

open access: yesAdvanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang   +3 more
wiley   +1 more source

A fruitful fly forward : the role of the fly in drug discovery for neurodegeneration [PDF]

open access: yes, 2014
AD, Alzheimer’s disease; APP, amyloid precursor protein; BBB, blood brain barrier; GFP, green fluorescent protein; HTS, high-throughput screening; HD, Huntington’s disease; LB, Lewy bodies; PD, Parkinson’s disease; PolyQ, Polyglutamine; RNAi, RNA ...
Briffa, Michelle   +2 more
core   +1 more source

Poka: A Necro‐Robot Beetle with a Measured Payload Ratio of 6847%

open access: yesAdvanced Robotics Research, EarlyView.
Here, Poka, a necro‐robot beetle with the ability to carry more than 68 times its own weight, is introduced, making it also a walking robot with the highest payload ratio measured to date. This paper is concerned with the design, manufacture and validation of ‘Poka', a novel millimetre‐scale necro‐robot aimed at bridging the performance gap between ...
Yordan Tsvetkov, Parvez Alam
wiley   +1 more source

The impact of SPARC on age-related cardiac dysfunction and fibrosis in Drosophila [PDF]

open access: yes, 2018
Tissue fibrosis, an accumulation of extracellular matrix proteins such as collagen, accompanies cardiac ageing in humans and this is linked to an increased risk of cardiac failure.
Hartley, Paul S.   +3 more
core   +1 more source

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

open access: yesAdvanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang   +14 more
wiley   +1 more source

Drosophila DNA-Binding Proteins in Polycomb Repression

open access: yesEpigenomes, 2018
The formation of individual gene expression patterns in different cell types is required during differentiation and development of multicellular organisms.
Maksim Erokhin   +2 more
doaj   +1 more source

Evolution of secondary cell number and position in the Drosophila accessory gland.

open access: yesPLoS ONE, 2023
In animals with internal fertilization, males transfer gametes and seminal fluid during copulation, both of which are required for successful reproduction. In Drosophila and other insects, seminal fluid is produced in the paired accessory gland (AG), the
Yoko A Takashima   +2 more
doaj   +1 more source

A Mammalian Homolog of Drosophila melanogaster Transcriptional Coactivator Intersex Is a Subunit of the Mammalian Mediator Complex [PDF]

open access: yes, 2003
The multiprotein Mediator complex is a coactivator required for transcriptional activation of RNA polymerase II transcribed genes by DNA binding transcription factors.
Banks, Charles A. S.   +7 more
core   +1 more source

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