Results 31 to 40 of about 1,612 (203)

Droxidopa in neurogenic orthostatic hypotension [PDF]

Expert Review of Cardiovascular Therapy, 2015
Neurogenic orthostatic hypotension (nOH) is a fall in blood pressure (BP) on standing due to reduced norepinephrine release from sympathetic nerve terminals. nOH is a feature of several neurological disorders that affect the autonomic nervous system, most notably Parkinson disease (PD), multiple system atrophy (MSA), pure autonomic failure (PAF), and ...
Horacio, Kaufmann, Lucy, Norcliffe-Kaufmann, Jose-Alberto, Palma   +2 more
openaire   +2 more sources

Predicting the duration of action of β2‐adrenergic receptor agonists: Ligand and structure‐based approaches

Molecular Informatics, Volume 42, Issue 12, December 2023., 2023
Abstract Agonists of the β2 adrenergic receptor (ADRB2) are an important class of medications used for the treatment of respiratory diseases. They can be classified as short acting (SABA) or long acting (LABA), with each class playing a different role in patient management.
Luca Chiesa, Emilie Sick, Esther Kellenberger   +2 more
wiley   +1 more source

Autonomic dysregulation in multiple sclerosis [PDF]

, 2015
Multiple sclerosis (MS) is a chronic, progressive central neurological disease characterized by inflammation and demyelination. In patients with MS, dysregulation of the autonomic nervous system may present with various clinical symptoms including ...
Adrienn Sárközi, Alexandra Pintér, Ashtari, Bakke, Barak, Bemelmans, Ben Illigens, Chen, Cil, Cox, Domonkos Cseh, Donze, Dykstra, el-Maghraby, Glick, Hartmann, Hinds, Hornby, MacDonald, Nicholas, Ritvo, Staerman, Timo Siepmann, Tombul, Trenova, Valleroy, Vieira, Zemishlany   +27 more
core   +1 more source

Rasagiline does not exacerbate autonomic blood pressure dysregulation in early or mild Parkinson’s disease

Clinical Parkinsonism & Related Disorders, 2022
Introduction: Orthostatic hypotension (OH) and abnormal blood pressure (BP) fluctuations occur mainly due to noradrenergic dysfunction and are clinically important in patients with Parkinson’s disease (PD). They lead to impairments of cognition function,
Hisayoshi Oka, Renpei Sengoku, Atsuo Nakahara, Mikihiro Yamazaki   +3 more
doaj   +1 more source

Prescription rate of medications potentially contributing to lower urinary tract symptoms and detection of adverse reactions by prescription sequence symmetry analysis [PDF]

, 2015
BACKGROUND: The lower urinary tract symptoms (LUTS) increases with age and can have a significant effect on the quality of life of the patients. Elderly patients, who are often characterized by a decline in physiological functional and polypharmacy, are ...
Fumihiko Ando, Kanako Hashimoto, Keisuke Nagase, Kunizo Arai, Masako Hashimoto, Yoshiaki Kimura   +5 more
core   +2 more sources

DNetDB: The human disease network database based on dysfunctional regulation mechanism [PDF]

, 2016
Additional analysis and concepts explanation. This file contains 1) comparison of DNetDB and the results of differential expression analysis (DEA-) based method ; 2) comparison of DNetDB and traditional disease classification; 3) negative disease ...
Fu-Yan Wang, Jia-Wei Peng, Jing Yang, Shao-You Yang, Shi-Nuo Wang, Su-Juan Wu, Ting Qi, Yi-Xue Li, Yu-Xing Song, Yuan-Yuan Li   +9 more
core   +2 more sources

Clinical management of neurogenic orthostatic hypotension

Annals of Movement Disorders, 2019
Neurogenic orthostatic hypotension is a common disorder often seen in elderly patients affected with neurodegenerative disorders and peripheral neuropathies.
Malligurki Raghurama Rukmani, Ravi Yadav, Pramod K Pal, Talakad N Sathyaprabha   +3 more
doaj   +1 more source

Persistent unexplained chest pain and dyspnea in a patient with coronary artery disease: a case report

BMC Cardiovascular Disorders, 2020
Background Neurogenic orthostatic hypotension, a sustained decrease in blood pressure upon standing, is caused by autonomic nervous system failure and characterized by an insufficient increase in heart rate needed to maintain blood pressure upon standing.
Sameh K. Mobarek
doaj   +1 more source

Sleep Architecture Alterations Following High-Dose Steroid Pulse Therapy: A Pilot Study Using a Portable Electroencephalogram-Based Device. [PDF]

Neuropsychopharmacol Rep
High‐dose steroid pulse therapy markedly reduces total sleep time, REM, and NREM sleep, as objectively demonstrated for the first time using a portable EEG‐based device. ABSTRACT Background Sleep disturbance is a common side effect of high‐dose steroid pulse therapy (SPT).
Endo H, Shigetsura Y, Chahara M, Kido K, Nakanishi E, Ueda S, Kimura K, Kuzuya A, Kawashima H, Matsumoto R, Tsuda M, Nakagawa S, Terada T.   +12 more
europepmc   +2 more sources

Treatment of Orthostatic Hypotension Due to Autonomic Dysfunction (Neurogenic Orthostatic Hypotension) in a Patient with Cardiovascular Disease and Parkinson's Disease

Cardiology and Therapy, 2019
Introduction The prevalence of neurogenic orthostatic hypotension (nOH) increases with age and is associated with autonomic failure in neurodegenerative diseases (e.g., Parkinson's disease).
Peter A. McCullough
doaj   +1 more source