Supine plasma NE predicts the pressor response to droxidopa in neurogenic orthostatic hypotension [PDF]
To test whether the plasma levels of norepinephrine (NE) in patients with neurogenic orthostatic hypotension (nOH) predict their pressor response to droxidopa.This was an observational study, which included patients with nOH. All patients had standardized autonomic function testing including determination of venous plasma catecholamine levels drawn ...
Jose‐Alberto Palma+3 more
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Cardiovascular Safety of Droxidopa in Patients With Symptomatic Neurogenic Orthostatic Hypotension [PDF]
The norepinephrine prodrug droxidopa improves symptoms of neurogenic orthostatic hypotension, a condition that is associated with diseases of neurogenic autonomic failure (e.g., Parkinson disease, multiple system atrophy, pure autonomic failure). These conditions are more prevalent in older patients who also have cardiovascular co-morbidities.
Adam Ziemann+4 more
openaire +3 more sources
Initiating droxidopa for neurogenic orthostatic hypotension in a patient with Parkinson disease [PDF]
Daniel O. Claassen, Mark Lew
openalex +3 more sources
Prescription rate of medications potentially contributing to lower urinary tract symptoms and detection of adverse reactions by prescription sequence symmetry analysis [PDF]
BACKGROUND: The lower urinary tract symptoms (LUTS) increases with age and can have a significant effect on the quality of life of the patients. Elderly patients, who are often characterized by a decline in physiological functional and polypharmacy, are ...
Fumihiko Ando+5 more
core +2 more sources
Development of a combined database / in silico pipeline for the investigation of novel approaches for precision medicine [PDF]
This project investigates how integrated in silico approaches can be developed to advance precision medicine. A novel bioinformatics database was created and implemented.
HENRY ASOMUGHA
core
Electrochemical determination of amaranth in food samples by using modified electrode [PDF]
In this paper, a new electrochemical sensor was reported for the determination of amaranth in drink soft. In this sensor, activated carbon-Co3O4 nanocomposite (AC-Co3O4) was employed as electrode modifying material.
Baghelani, Yar-Mohammad+4 more
core +2 more sources
Method development and validation of droxidopa by HPLC technique
The purpose of this work is to develop and validate stability, indicating reverse phase High-performance liquid chromatography (HPLC) method for the rapid and precise determination of droxidopa in its pure form and formulations. A simple, fast, accurate and economical way has been developed and validated for the quantification of droxidopa by HPLC ...
Nalini C N+3 more
openaire +2 more sources
New insights into orthostatic hypotension in multiple system atrophy: a European multicentre cohort study [PDF]
Objectives: Orthostatic hypotension (OH) is a key feature of multiple system atrophy (MSA), a fatal progressive neurodegenerative disorder associated with autonomic failure, parkinsonism and ataxia.
Calandra Buonara, G.+19 more
core +1 more source
Formaldehyde 2% is not a useful means of detecting allergy to formaldehyde releasers- results of theESSCAnetwork, 2015-2018 [PDF]
BACKGROUND Studies suggest that patch testing with formaldehyde releasers (FRs) gives significant additional information to formaldehyde 1% aq. and should be considered for addition to the European baseline series (EBS).
Ballmer-Weber, Barbara+21 more
core +2 more sources
New evidence on the management of Lewy body dementia [PDF]
This is the author accepted manuscript. The final version is available from Elsevier via the DOI in this recordNote that the article title of the accepted author manuscript is different to that of the final published version.Dementia with Lewy bodies and
Allan, LM+8 more
core +1 more source