Results 71 to 80 of about 1,868 (233)
Blood, 2021 Background Orthostatic hypotension due to autonomic dysfunction is a well-known complication of light chain (AL) amyloidosis, which can become progressively debilitating and difficult to manage.
Jorge Nicolas Ruiz Lopez +6 more
semanticscholar +1 more source
Reflex syncope: Diagnosis and treatment
, 2017 For the diagnosis of reflex syncope, diligent history-building with the patient and a witness is required. In the Emergency Department (ED), the assessment of syncope is a challenge which may be addressed by an ED Observation Unit or by a referral to a ...
Sutton, R
core +2 more sources
Effects of midodrine and L-NAME on systemic and cerebral hemodynamics during cognitive activation in spinal cord injury and intact controls [PDF]
, 2016 This is the published version.We previously showed that increases in mean arterial pressure (MAP) following administration of midodrine hydrochloride (MH) and nitro-L-arginine methyl ester (L-NAME) resulted in increased mean cerebral blood flow velocity (
Bauman, William A. +3 more
core +1 more source
Is Droxidopa Safe and Effective in Reducing Symptoms of Neurogenic Orthostatic Hypotension? [PDF]
, 2017 Objective: The objective of this selective EBM review is to determine whether or not droxidopa is safe and effective in reducing the symptoms of neurogenic orthostatic hypotension.
Longo, Nicholas W
core +1 more source
Cognitive function in peripheral autonomic disorders [PDF]
, 2014 aims of the current study were 1) to evaluate global cognitive function in patients with autonomic failure (AF) of peripheral origin and 2) to investigate the effect of a documented fall in blood pressure (BP) fulfilling the criteria for orthostatic ...
Calandra-Buonaura, G. +6 more
core +2 more sources
Efficacy of triple neurotransmitter replacement therapy for patients with progressive supranuclear palsy [PDF]
, 2021 【目的】有効な治療法の確立されていない神経変性疾患である進行性核上性麻痺（ progressive supranuclear palsy: PSP）に対し，障害されているとされる，ドーパミン・ノルアドレナリン・アセチルコリンの３系統の神経伝達物質を同時に補充し，運動機能・認知機能を評価し有効性を明らかにする。 【方法】The National Institute of Neurological Disorders and Stroke and Society for Progressive ...
小澤, 忠嗣, 藤本, 茂
core
Norepinephrine: the next therapeutics frontier for Parkinson\u27s disease [PDF]
, 2012 Tissue concentrations of norepinephrine (NE) are markedly decreased in various regions of the Parkinson\u27s disease (PD) brain. As in the substantia nigra pars compacta, neuronal dropout and Lewy bodies are prominent changes affecting the locus ...
LeWitt, Peter A
core +1 more source
Annals of Neurology, Volume 96, Issue 3, Page 423-440, September 2024.Amyloid neuropathy is caused by deposition of insoluble β‐pleated amyloid sheets in the peripheral nervous system. It is most common in: (1) light‐chain amyloidosis, a clonal non‐proliferative plasma cell disorder in which fragments of immunoglobulin, light or heavy chain, deposit in tissues, and (2) hereditary transthyretin (ATTRv) amyloidosis, a ...
Pitcha Chompoopong +3 more
wiley +1 more source
Istradefylline/L‐DOPA Parkinson's disease therapy and energy coupling
Neurology and Clinical Neuroscience, Volume 12, Issue 5, Page 296-305, September 2024.Abstract Background Both dopamine and adenosine are physiologically involved in cellular energy metabolism. Aim Novel approaches targeting delaying progression strategies for Parkinson's disease (PD) examined the effects of long‐term use of A2AR antagonist/istradefylline (IST) adjunct to L‐DOPA (LD), nutshell IST‐LD, with an expected energy coupling ...
Naomi Kanzato +2 more
wiley +1 more source
Neural Plasticity, 2016 In the present study, we investigated whether restoring descending noradrenergic inhibitory tone can attenuate pain in a PD rat model, which was established by stereotaxic infusion of 6-hydroxydopamine (6-OHDA) into the bilateral striatum (CPu).
Lei-Fang Cao +8 more
doaj +1 more source