Results 81 to 90 of about 1,868 (233)

Associations of vitamin D receptor activators and calcimimetics with falls and effect modifications by physical activity: A prospective cohort study on the Japan Dialysis Outcomes and Practice Patterns Study

Therapeutic Apheresis and Dialysis, Volume 28, Issue 4, Page 547-556, August 2024.
Abstract Introduction This study aimed to examine the associations of vitamin D receptor activators (VDRA) and calcimimetics use with falls. Methods This is a prospective cohort study on hemodialysis patients in the Japan Dialysis Outcomes and Practice Patterns Study. We excluded those who were unable to walk.
Miho Murashima, Ryohei Yamamoto, Eiichiro Kanda, Noriaki Kurita, Hisashi Noma, Takayuki Hamano, Masafumi Fukagawa   +6 more
wiley   +1 more source

Disautonomia: Uma Condição Esquecida – Parte 1 [PDF]

Arquivos Brasileiros de Cardiologia
Resumo – Pontos Essenciais O termo disautonomia abrange um conjunto de condições clínicas com características e prognósticos distintos. Classificam-se em síndromes reflexas, síndrome postural ortostática taquicardizante (SPOT), síndrome da fadiga crônica,
Eduardo Arrais Rocha, Niraj Mehta, Maria Zildany Pinheiro Távora-Mehta, Camila Ferreira Roncari, Alan Alves de Lima Cidrão, Jorge Elias Neto   +5 more
doaj   +3 more sources

DNetDB: The human disease network database based on dysfunctional regulation mechanism [PDF]

, 2016
Additional analysis and concepts explanation. This file contains 1) comparison of DNetDB and the results of differential expression analysis (DEA-) based method ; 2) comparison of DNetDB and traditional disease classification; 3) negative disease ...
Fu-Yan Wang, Jia-Wei Peng, Jing Yang, Shao-You Yang, Shi-Nuo Wang, Su-Juan Wu, Ting Qi, Yi-Xue Li, Yu-Xing Song, Yuan-Yuan Li   +9 more
core   +2 more sources

Supportive Care and Symptom Management for Patients With Immunoglobulin Light Chain (AL) Amyloidosis [PDF]

, 2022
Immunoglobulin light chain (AL) amyloidosis is a disorder of clonal plasma cells characterized by deposition of amyloid fibrils in a variety of tissues, leading to end-organ injury.
Byku, Mirnela, Hladik, Gerald A., Jain, Koyal, Jensen, Christopher E., Traub, Rebecca E., Tuchman, Sascha A.   +5 more
core   +2 more sources

Efficacy and Safety of Elobixibat in Parkinson's Disease with Chronic Constipation: CONST‐PD Study

Movement Disorders Clinical Practice, Volume 11, Issue 4, Page 352-362, April 2024.
Abstract Background Chronic constipation is a common digestive complication of Parkinson's disease (PD). Objectives To verify the usefulness of elobixibat, an ileal bile acid transporter inhibitor, for chronic constipation in PD. Methods This double‐blind, placebo‐controlled study consisted of a 2‐week observation/washout period and a 4‐week treatment ...
Taku Hatano, Genko Oyama, Yasushi Shimo, Kotaro Ogaki, Noriko Nishikawa, Ryota Nakamura, Taiji Tsunemi, Takashi Ogawa, Hiroto Eguchi, Kensuke Daida, Naohide Kurita, Shin‐ichi Ueno, Jiro Fukae, Wataru Sako, Kenta Shiina, Sho Nakajima, Yutaka Oji, Ryo Wakamori, Shinji Saiki, Kenya Nishioka, Ayami Okuzumi, Daisuke Taniguchi, Haruka Takeshige‐Amano, Atsuhito Fuse, Asuka Nakajima, Masayoshi Kano, Hikaru Kamo, Yuri Yamashita, Atsuhiko Shindo, Naotake Yanagisawa, Nobutaka Hattori   +30 more
wiley   +1 more source

Rasagiline does not exacerbate autonomic blood pressure dysregulation in early or mild Parkinson’s disease

Clinical Parkinsonism & Related Disorders, 2022
Introduction: Orthostatic hypotension (OH) and abnormal blood pressure (BP) fluctuations occur mainly due to noradrenergic dysfunction and are clinically important in patients with Parkinson’s disease (PD). They lead to impairments of cognition function,
Hisayoshi Oka, Renpei Sengoku, Atsuo Nakahara, Mikihiro Yamazaki   +3 more
doaj  

Distinguishing Multiple System Atrophy vs Parkinson’s Disease in an African American Woman [PDF]

, 2022
An 87-year-old African American woman with a past medical history of atrial fibrillation on warfarin and peripheral neuropathy with a family history of myasthenia gravis presented to the Emergency Department.
Kane, Mahoua, Smith, Rebecca, Venkataraman, Venkat   +2 more
core   +1 more source

Diagnosis and treatment of hereditary transthyretin amyloidosis with polyneuropathy in the United States: Recommendations from a panel of experts

Muscle &Nerve, Volume 69, Issue 3, Page 273-287, March 2024.
Abstract Hereditary transthyretin (ATTRv; v for variant) amyloidosis is a rare, multisystem, progressive, and fatal disease in which polyneuropathy is a cardinal manifestation. Due to a lack of United States (US)‐specific guidance on ATTRv amyloidosis with polyneuropathy, a panel of US‐based expert clinicians convened to address identification ...
Chafic Karam, Michelle L. Mauermann, Alejandra Gonzalez‐Duarte, Michelle C. Kaku, Senda Ajroud‐Driss, Thomas H. Brannagan III, Michael Polydefkis   +6 more
wiley   +1 more source

MIBG Predicts Falls in PD [PDF]

, 2021
Background: Falls are associated with poor prognosis in patients with Parkinson's disease (PD). Although several factors related to falls were reported in patients with PD, objective predictors of falls are not identified.
Furukawa, Takahiro, Haji, Shotaro, Harada, Masafumi, Izumi, Yuishin, Kaji, Ryuji, Murakami, Nagahisa, Otomi, Yoichi, Otsuka, Hideki, Sako, Wataru   +8 more
core  

Impact of the Norepinephrine Prodrug Droxidopa on the QTc Interval in Healthy Individuals [PDF]

Clinical Pharmacology in Drug Development, 2017
AbstractA double‐blind, 4‐period crossover study (NCT01327066) was conducted to assess the effect of the novel norepinephrine prodrug droxidopa on the QT interval in in healthy subjects. Subjects were randomized to receive a single dose of droxidopa 600 mg (maximal dose) and 2000 mg (supratherapeutic dose) compared with the positive control ...
L. Arthur Hewitt, Ali Mehdirad, William B. White   +2 more
openaire   +3 more sources