Results 71 to 80 of about 6,612,897 (317)

Herbal - Synthetic Drug Interactions

open access: yesMagna Medika, 2023
Background:  Herbal medicine is currently one of the therapeutic options chosen by the community because it is considered relatively safer and has minimal side effects.
Kintoko Kintoko   +7 more
doaj   +1 more source

Pharmacodynamic Drug–Drug Interactions

open access: yesClinical pharmacology and therapy, 2019
Pharmacodynamic drug–drug interactions (DDIs) occur when the pharmacological effect of one drug is altered by that of another drug in a combination regimen. DDIs often are classified as synergistic, additive, or antagonistic in nature, albeit these terms
Jin Niu, R. Straubinger, D. Mager
semanticscholar   +1 more source

Pharmacokinetic-Based Drug–Drug Interactions with Anaplastic Lymphoma Kinase Inhibitors: A Review

open access: yesDrug Design, Development and Therapy, 2020
Anaplastic lymphoma kinase (ALK) inhibitors are important treatment options for non-small-cell lung cancer (NSCLC), associated with ALK gene rearrangement.
Dehua Zhao   +4 more
semanticscholar   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

Evaluation of resources for analyzing drug interactions

open access: yesJournal of the Medical Library Association, 2017
Objective: The research sought to evaluate seven drug information resources, specifically designed for analyzing drug interactions for scope, completeness, and ease of use, and determine the consistency of content among the seven resources.
Risha I. Patel, Robert D. Beckett
doaj   +1 more source

Pilot study: Evaluation of potential drug–drug interactions in hospitalized pediatric patients

open access: yesPediatrics and Neonatology, 2020
Purpose: Evaluate the type and severity of potential drug-drug interactions and identify risk factors involved, in pediatric patients admitted in a hospital setting.
Fabiola Medina-Barajas   +6 more
doaj   +1 more source

Prevalence of potential drug–drug interactions in outpatients of a general hospital in China: a retrospective investigation

open access: yesInternational Journal of Clinical Pharmacy, 2020
Background Potential drug–drug interactions are important factors resulting in adverse drug reactions or therapeutic failure. Therefore, potential drug–drug interactions need to be identified to prevent the related risk and improve drug safety. Objective
Weifang Ren   +6 more
semanticscholar   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

A pilot study to determine the occurrence of concomitant diseases and drug intake in patients on antituberculosis therapy

open access: yesJournal of Family Medicine and Primary Care, 2018
Introduction: Altered pharmacokinetics of antituberculosis (anti-TB) drugs due to interaction with non-TB medications or concomitant diseases may lead to suboptimal plasma levels of the affected drugs and hence contribute to the emergence of drug ...
Ratinder Jhaj   +3 more
doaj   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

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