Results 91 to 100 of about 5,801,403 (265)
Victorian Drug Household Survey, 1993
, 2019 The Victorian Drug Household Survey (VDHS) was conducted as an extension to the fourth National Campaign Against Drugs and Alcohol (NCADA) National Drug Household Survey (NDHS).
Harrison, Stanford
core +1 more source
Navigating Drug–Drug Interactions in Clinical Drug Development: A Tutorial
Clinical and Translational ScienceThis tutorial provides essential guidelines and insights, in addition to regulatory guidance, for the evaluation of drug–drug interactions (DDIs), with a focus on the tools and timing of assessment critical for effective management of inclusion/exclusion
Jesmin Lohy Das +2 more
doaj +1 more source
Drug–Drug Interactions in Patients with Brucellosis: A Retrospective Analysis
Mediterranean Journal of Infection, Microbes and AntimicrobialsIntroduction: The prolonged duration of drug treatment and the need for combination therapy in brucellosis increase the risk of drug-related problems. One of the most significant drug-related problems is drug–drug interactions.
Bahar Çelebi +3 more
doaj +1 more source
Metabolism, Transport and Drug–Drug Interactions of Silymarin
Molecules, 2019 Silymarin, the extract of milk thistle, and its major active flavonolignan silybin, are common products widely used in the phytotherapy of liver diseases.
Ying Xie +3 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Drug-drug interactions : from knowledge base to clinical impact
, 2014 Drug usage has increased steadily, and the more drugs used, the higher the risk for adverse effects or loss of effect due to drug-drug interactions. For drug prescribers it is difficult to know what drugs a patient is taking and whether they interact ...
Marine Andersson (18690100)
core +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
, 2016 The UK Medicines and Healthcare products Regulatory Agency received a Coroner’s report that raised concerns about a suspected drug interaction between citalopram and cocaine after the death of a man due to subarachnoid haemorrhage.
core
A STUDY ON POTENTIAL DRUG - DRUG INTERACTIONS IN MEDICINE DEPARTMENT OF A MULTI SPECIALTY TEACHING HOSPITAL [PDF]
, 2017 Aim of study: Drug-drug interaction (DDI) occurs when two or more drugs are simultaneously administered, where the effect of one drug is altered by the concomitant use of another drug.
Bhat, Tanmay +2 more
core +1 more source