Results 11 to 20 of about 94,701 (219)
Drug-drug interactions in the hospital [PDF]
, 2007 Introduction Drug interaction screening programs are an important tool to check prescriptions of multiple drugs for potential drug-drug interactions (pDDIs). Several programs are available on the market.
Vonbach, Priska
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Big Data Management in Drug–Drug Interaction: A Modern Deep Learning Approach for Smart Healthcare [PDF]
, 2022 The detection and classification of drug–drug interactions (DDI) from existing data are of high importance because recent reports show that DDIs are among the major causes of hospital-acquired conditions and readmissions and are also necessary for ...
Hafiz Suliman Munawar +11 more
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Pharmaceutics, 2022 The poor aqueous solubility and/or permeability and thereby limited bioavailability largely restricts the pharmaco-therapeutic implications of potent anticancer drugs such as methotrexate (MTX).
Bhupendra Raj Giri +5 more
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Prediction of human drug clearance and anticipation of clinical drug-drug interaction potential from in vitro drug transport studies [PDF]
, 2014 A major concern in drug development is the characterization of new molecular entities (NMEs) with respect to their safety and efficacy. Both factors are determined by the drug’s exposure within the body which itself is affected by drug clearance ...
Kunze, Annett
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Pharmaceutics, 2022 Ursodeoxycholate (UDCA) has low oral bioavailability and pH-dependent solubility and permeability. Thus, we developed a pH-modified extended-release formulation of UDCA using Na2CO3 as the alkalizing agent and hydroxypropyl methylcellulose (HPMC) as the ...
Jaehyeok Lee +5 more
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Potential drug interactions : exposure and management in hospital and ambulatory settings [PDF]
, 2006 Health care professionals are responsible to ensure safe dispensing and use of drug regimens involving the use of drug combinations that may interact and cause serious adverse events.
Indermitte, Jörg Lorenz
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Recent Advances in Doxorubicin Formulation to Enhance Pharmacokinetics and Tumor Targeting
Pharmaceuticals, 2023 Doxorubicin (DOX), a widely used drug in cancer chemotherapy, induces cell death via multiple intracellular interactions, generating reactive oxygen species and DNA-adducted configurations that induce apoptosis, topoisomerase II inhibition, and histone ...
Jihoon Lee, Min-Koo Choi, Im-Sook Song
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Digoxin + Cyclosporine - contextualized potential drug-drug interaction clinical algorithm
, 2020 An algorithm developed for research purposes that summarizes the potential drug-drug interaction between digoxin and cyclosporine. The information is not advice, and should not be treated as such.
Contributors to the A Minimum Representation of Potential Drug-Drug Interaction Knowledge and Evidence - Technical and User-centered Foundation Specification
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Improving Drug–Drug Interaction Extraction with Gaussian Noise
Pharmaceutics, 2023 Drug–Drug Interactions (DDIs) produce essential and valuable insights for healthcare professionals, since they provide data on the impact of concurrent administration of medications to patients during therapy.
Marco Molina +2 more
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Drug-drug interaction-related uncontrolled glycemia
Journal of Pharmacy and Bioallied Sciences, 2017 Context: The literature of drug-drug interaction (DDI)-related uncontrolled causality, and preventability of DDI-induced UCG (HbA1c >7%) in outpatients glycemia (UCG) among outpatients with Type 2 diabetes mellitus is still limited. Aims: The aim of this
Mohamed Anwar Hammad +6 more
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