Results 261 to 270 of about 6,566,618 (306)

Drug—Drug Interactions in the Elderly

Annals of Pharmacotherapy, 2002
OBJECTIVE: To detect the frequency of potential drug—drug interactions (DDIs) in an outpatient group of elderly people in 6 European countries, as well as to describe differences among countries. DATA SOURCES AND METHODS: Drug use data
Ingeborg K Björkman, Johan Fastbom, Ingrid K Schmidt, Cecilia B Bernsten, Cecilia B Bernsten, Ingeborg K Björkman, Margarida Caramona, Grainne Crealey, Bente Frøkjær, Erika Grünberger, Tove Gustafsson, Martin Henman, Hanne Herborg, Carmel Hughes, James C McElnay, Maeve Magner, Foppe van Mil, Marion Schaeffer, Sonia Silva, Birthe Søndergaard, Ian Sturgess, Dick Tromp, Lisa Vivero, Almut Winterstein   +23 more
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CARDIOVASCULAR DRUG-DRUG INTERACTIONS

Cardiology Clinics, 2001
The drug-drug interactions discussed in this article have either documented or suspected clinical relevance for patients with cardiovascular disease and the clinician involved in the care of these patients. Oftentimes, drug-drug interactions are difficult, if not impossible, to predict because of the high degree of interpatient variability in drug ...
J R, Anderson, J J, Nawarskas
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Identification of Serious Drug–Drug Interactions: Results of the Partnership to Prevent Drug–Drug Interactions

Journal of the American Pharmacists Association, 2004
To develop a list of clinically important drug-drug interactions (DDIs) likely to be encountered in community and ambulatory pharmacy settings and detected by a computerized pharmacy system.Cross-sectional, one-time evaluation.United States in fall 2001.An expert panel comprising two physicians, two clinical pharmacists, and an expert on DDIs ...
Daniel C, Malone, Jacob, Abarca, Philip D, Hansten, Amy J, Grizzle, Edward P, Armstrong, Robin C, Van Bergen, Babette S, Duncan-Edgar, Steven L, Solomon, Richard B, Lipton   +8 more
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Drug-Drug Interactions with Antipsychotics

CNS Spectrums, 2007
Recognizing drug-drug interactions (DDIs) has become increasingly important as the country's demographics have aged, resulting in more complex medication regimens. Budnitz and colleagues highlighted the frequency of adverse drug reactions (ADRs) and the substantial morbidity that results.
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Avoiding Drug-Drug Interactions

Chemotherapy, 2009
<i>Background:</i> Drugs may be prescribed in combinations causing drug-drug interactions (DDI) and adverse drug reactions (ADR), resulting in hospital care. <i>Methods:</i> To provide prescribers of drug therapy with a better knowledge of individuals’ current drug therapy, governments have started to collect prescribing data ...
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Drug-Drug Interaction

JAMA: The Journal of the American Medical Association, 1969
Interference With the Delivery of Drugs to Their Sites of Action An increasing number of mechanisms have been described whereby one drug can modify profoundly the action of another. In some of these interactions, the therapeutic effect of a drug may be blocked when another agent prevents it from reaching the site of its pharmacologic action ...
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Transporter-Mediated Drug–Drug Interactions

Clinical Pharmacology & Therapeutics, 2011
Transporters are membrane-bound proteins that control the access of endogenous and xenobiotics (drugs) to various sites in the human body. They influence drug pharmacokinetics and pharmacodynamics (both benefit and risk) by affecting a drug's absorption, distribution, metabolism (via control of access to metabolizing enzymes), and excretion (ADME) and ...
L, Zhang, S-M, Huang, L J, Lesko
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Overview: Pharmacokinetic Drug-Drug Interactions

1997
Publisher Summary With the increasing median age of the population, and the now known effectiveness of multiple-therapy regimens for viral diseases, for example, HIV, cancer, cardiovascular diseases, and infectious diseases, exposure of a patient to multiple drugs is a common rather than rare occurrence.
A P, Li, M, Jurima-Romet
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Drug–drug interactions

Abstract Drug–drug interactions may be pharmacokinetic or pharmacodynamic, which may or may not lead to differences in the clinical responses when the individual drugs are administered alone. The characterization of the interactions is highlighted with regards to altered absorption, distribution, transport, induction/ inhibition and ...
Phil Ambery, Adrian Kilcoyne, Daniel O’Connor   +2 more
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Cocaine Drug-Drug Interactions

Journal of Clinical Psychopharmacology, 1992
B F, Sands, D A, Ciraulo
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