MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru +13 more
wiley +1 more source
Comparative thromboembolic risk and polypharmacy-related drug-drug interaction signals among antidiabetic medications: a large-scale FAERS pharmacovigilance study. [PDF]
Bafail D, Ghazal H.
europepmc +1 more source
Enhanced CYP2C19-mediated drug-drug interaction risk with escitalopram in geriatric populations. [PDF]
Byoun S +7 more
europepmc +1 more source
CMCL-DDI: Pharmacophore-aware cross-view contrastive learning for drug-drug interaction prediction. [PDF]
Han Y, Du L.
europepmc +1 more source
Drug-drug interaction between ticagrelor and fazamorexant: pharmacokinetic alterations in healthy subjects from a phase I, open-label, fixed-sequence study. [PDF]
Huang X +5 more
europepmc +1 more source
Polypharmacy and Drug-Drug Interaction Architecture in Hospitalized Cardiovascular Patients: Insights from Real-World Analysis. [PDF]
Radu AF +9 more
europepmc +1 more source
Pharmacokinetic drug-drug interaction between the COVID-19 3CL protease inhibitor GST-HG171 and itraconazole in healthy subjects. [PDF]
Li X +11 more
europepmc +1 more source
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A drug interaction occurs when the effects of a drug are altered by the effects of another drug, a vaccine, herb, foodstuff, or device. In drug–drug interactions, a precipitant drug increases or reduces the effects of an object drug by pharmaceutical, pharmacokinetic, or pharmacodynamic mechanisms.
Lopamudra Chowdhury, Om Singh
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Drug–drug interaction with statins
Expert Review of Clinical Pharmacology, 20083-hydroxy-3-methyl-glutaryl (HMG)-CoA reductase inhibitors (the so-called statins: atorvastatin, fluvastatin, pravastatin, lovastatin, rosuvastatin and simvastatin) are a well-established class of drugs in the treatment of hypercholesterolemia. Statin monotherapy is generally well tolerated, with a low frequency of adverse events.
A. Corsini, S. Bellosta
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