Results 1 to 10 of about 1,013,692 (152)
Tutorial Drug–Drug Interactions [PDF]
Clinical and Translational ScienceEdward M. Sellers
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Drug-drug interactions with raltegravir
European Journal of Medical Research, 2009 Objective To review all currently published drug-drug interaction studies with the HIV-integrase inhibitor raltegravir. Methods A PubMed search was conducted for all published reports up to August 1, 2009 as well as a review of updated European and US ...
Burger David M
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Role of metabolites in drug-drug interactions. [PDF]
Drug Metab PharmacokinetSince the publication of the metabolites in safety testing (MIST) guidance by the US FDA in 2009, there has been continuous interest and expansion in research aimed at predicting and characterizing circulating metabolites. Several systematic reviews and original research articles have been published to assess the role of metabolites in drug-drug ...
Isoherranen N.
europepmc +3 more sources
Pharmaceuticals, 2021 Drug interactions are a well-known cause of adverse drug events, and drug interaction databases can help the clinician to recognize and avoid such interactions and their adverse events. However, not every interaction leads to an adverse drug event.
Martina Hahn, Sibylle C. Roll
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Clinical Evaluation of Drug–Drug Interactions With Aficamten [PDF]
Clinical and Translational ScienceAficamten is a next‐in‐class small molecule cardiac myosin inhibitor that was recently approved by the United States Food and Drug Administration (FDA) for the treatment of symptomatic obstructive hypertrophic cardiomyopathy (oHCM).
Neha Maharao +11 more
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Navigating Drug–Drug Interactions in Clinical Drug Development: A Tutorial [PDF]
Clinical and Translational ScienceThis tutorial provides essential guidelines and insights, in addition to regulatory guidance, for the evaluation of drug–drug interactions (DDIs), with a focus on the tools and timing of assessment critical for effective management of inclusion/exclusion
Jesmin Lohy Das +2 more
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PRELIMINARY INVESTIGATION ON THE PRODUCTION OF SURFACE ACTIVE COMPOUNDS WITH ANTIMICROBIAL AND EMULSIFYING PROPERTIES BY BACILLUS CLAUSII AND LACTOBACILLUS RHAMNOSUS PROBIOTIC STRAINS [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2021 Surface active compounds (SACs) of bacterial origin are amphiphilic heteropolymers that may alter the interaction of gas-liquid, solid-liquid, and immiscible liquids surfaces, decrease the surface and interfacial tensions of liquids, and form stable ...
Marcus Dias-Souza +2 more
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Pharmacokinetic Drug–Drug Interactions and Herb–Drug Interactions
Pharmaceutics, 2021 Due to the growing use of herbal supplementation—ease of taking herbal supplements with therapeutics drugs (i [...]
Min-Koo Choi, Im-Sook Song
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NOACs: drug–drug interactions [PDF]
Canadian Medical Association Journal, 2016 We commend Fralick and colleagues for their article on drug interactions with rivaroxaban.[1][1] All novel oral anticoagulants (NOACs) were introduced as at least noninferior (in some cases superior) to warfarin.
Bartosz, Hudzik +2 more
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Predicting drug-target interactions using drug-drug interactions. [PDF]
PLoS ONE, 2013 Computational methods for predicting drug-target interactions have become important in drug research because they can help to reduce the time, cost, and failure rates for developing new drugs.
Shinhyuk Kim, Daeyong Jin, Hyunju Lee
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