Results 1 to 10 of about 5,634,975 (396)

Leveraging Omeprazole PBPK/PD Modeling to Inform Drug-Drug Interactions and Specific Recommendations for Pediatric Labeling. [PDF]

Pharmaceutics
Soliman A, Rodriguez-Vera L, Alarcia-Lacalle A, Pippa LF, Subhani S, Lukacova V, Duconge J, de Moraes NV, Vozmediano V.   +8 more
europepmc   +1 more source

Androgen receptor pathway inhibitors and drug-drug interactions in prostate cancer. [PDF]

ESMO Open
Bolek H, Yazgan SC, Yekedüz E, Kaymakcalan MD, McKay RR, Gillessen S, Ürün Y.   +6 more
europepmc   +1 more source

Application of Artificial Intelligence in Drug-Drug Interactions Prediction: A Review.

Journal of Chemical Information and Modeling, 2023
Drug-drug interactions (DDI) are a critical aspect of drug research that can have adverse effects on patients and can lead to serious consequences. Predicting these events accurately can significantly improve clinicians' ability to make better decisions ...
Yuanyuan Zhang, Zengqian Deng, Xiaoyu Xu, Yinfei Feng, Shang Junliang   +4 more
semanticscholar   +1 more source

Drug–drug interaction with statins

Expert Review of Clinical Pharmacology, 2008
3-hydroxy-3-methyl-glutaryl (HMG)-CoA reductase inhibitors (the so-called statins: atorvastatin, fluvastatin, pravastatin, lovastatin, rosuvastatin and simvastatin) are a well-established class of drugs in the treatment of hypercholesterolemia. Statin monotherapy is generally well tolerated, with a low frequency of adverse events.
A. Corsini, S. Bellosta
openaire   +3 more sources

Pharmacodynamic Drug–Drug Interactions

Drug Discovery and Evaluation: Methods in Clinical Pharmacology, 2018
Mingwu Zheng
openaire   +2 more sources

Drug—Drug Interactions in the Elderly

Annals of Pharmacotherapy, 2002
OBJECTIVE: To detect the frequency of potential drug—drug interactions (DDIs) in an outpatient group of elderly people in 6 European countries, as well as to describe differences among countries. DATA SOURCES AND METHODS: Drug use data were collected from 1601 elderly persons living in 6 European countries.
Ingeborg K Björkman, Johan Fastbom, Ingrid K Schmidt, Cecilia B Bernsten, Cecilia B Bernsten, Ingeborg K Björkman, Margarida Caramona, Grainne Crealey, Bente Frøkjær, Erika Grünberger, Tove Gustafsson, Martin Henman, Hanne Herborg, Carmel Hughes, James C McElnay, Maeve Magner, Foppe van Mil, Marion Schaeffer, Sonia Silva, Birthe Søndergaard, Ian Sturgess, Dick Tromp, Lisa Vivero, Almut Winterstein   +23 more
openaire   +3 more sources

Clinical Aspects of Transporter‐Mediated Drug–Drug Interactions

Clinical pharmacology and therapy, 2019
Drug transporters play an essential role in disposition and effects of multiple drugs. Plasma concentrations of the victim drug can be modified by drug–drug interactions occurring in enterocytes (e.g., P‐glycoprotein), hepatocytes (e.g., organic anion ...
A. Gessner, J. König, M. Fromm
semanticscholar   +1 more source

CARDIOVASCULAR DRUG-DRUG INTERACTIONS

Cardiology Clinics, 2001
The drug-drug interactions discussed in this article have either documented or suspected clinical relevance for patients with cardiovascular disease and the clinician involved in the care of these patients. Oftentimes, drug-drug interactions are difficult, if not impossible, to predict because of the high degree of interpatient variability in drug ...
James J. Nawarskas, Joe R. Anderson
openaire   +3 more sources

Tolvaptan efficacy and drug-drug interactions

Minerva Endocrinologica, 2020
Discussion of the presence of drug-drug interactions that may affect the efficacy of tolvaptan in hyponatremic patients affected by ...
Giampaolo Corti, Gregorio Basile, Gabriele Parenti, Filippo Bartalesi, Alessandro Peri, Alessandro Bartoloni, Matteo Piccica, Alberto Farese, Lisa Buci   +8 more
openaire   +4 more sources