Results 1 to 10 of about 1,121,296 (336)

Drug-drug interactions with raltegravir

open access: yesEuropean Journal of Medical Research, 2009
Objective To review all currently published drug-drug interaction studies with the HIV-integrase inhibitor raltegravir. Methods A PubMed search was conducted for all published reports up to August 1, 2009 as well as a review of updated European and US ...
Burger David M
doaj   +5 more sources

Drug-drug interactions of tacrolimus [PDF]

open access: yesHospital Pharmacology, 2015
Introduction: Tacrolimus, potent immunosupressive drug, has large inter- and intraindividual pharmacokinetic variability. The aim: The aim of this current topic is to describe the importance of tacrolimus drug-drug interactions.
Rančić Nemanja K.   +4 more
doaj   +4 more sources

Pharmacovigilance of Drug–Drug Interactions with Nirmatrelvir/Ritonavir [PDF]

open access: yesInfectious Diseases and Therapy
Introduction Nirmatrelvir/ritonavir (NMV/r) is approved in the United States (US) and more than 70 other countries for the treatment of mild to moderate COVID-19 in nonhospitalized adults at high risk for severe disease.
Victoria Hendrick   +8 more
doaj   +2 more sources

Drug–Drug Interactions of FXI Inhibitors: Clinical Relevance [PDF]

open access: yesHematology Reports
Inhibitors of the factor FXI represent a new class of anticoagulant agents that are facing clinical approval for the treatment of acute coronary syndrome (ACS), venous thromboembolism (VTE), and stroke prevention of atrial fibrillation (AF).
Nicola Ferri   +2 more
doaj   +2 more sources

Editorial: Drug-drug interactions in pharmacology

open access: yesFrontiers in Pharmacology, 2023
Simona Pichini   +3 more
doaj   +3 more sources

Pharmacokinetic Drug–Drug Interactions and Herb–Drug Interactions

open access: yesPharmaceutics, 2021
Due to the growing use of herbal supplementation—ease of taking herbal supplements with therapeutics drugs (i [...]
Min-Koo Choi, Im-Sook Song
doaj   +1 more source

Predicting drug-target interactions using drug-drug interactions. [PDF]

open access: yesPLoS ONE, 2013
Computational methods for predicting drug-target interactions have become important in drug research because they can help to reduce the time, cost, and failure rates for developing new drugs.
Shinhyuk Kim, Daeyong Jin, Hyunju Lee
doaj   +1 more source

Crystal structure correlations with the intrinsic thermodynamics of human carbonic anhydrase inhibitor binding [PDF]

open access: yesPeerJ, 2018
The structure-thermodynamics correlation analysis was performed for a series of fluorine- and chlorine-substituted benzenesulfonamide inhibitors binding to several human carbonic anhydrase (CA) isoforms.
Alexey Smirnov   +4 more
doaj   +2 more sources

The Influence of Pharmacogenetics on the Clinical Relevance of Pharmacokinetic Drug–Drug Interactions: Drug–Gene, Drug–Gene–Gene and Drug–Drug–Gene Interactions

open access: yesPharmaceuticals, 2021
Drug interactions are a well-known cause of adverse drug events, and drug interaction databases can help the clinician to recognize and avoid such interactions and their adverse events. However, not every interaction leads to an adverse drug event.
Martina Hahn, Sibylle C. Roll
doaj   +1 more source

Prevalence and Clinical Significance of Drug–Drug and Drug–Dietary Supplement Interactions among Patients Admitted for Cardiothoracic Surgery in Greece

open access: yesPharmaceutics, 2021
Background: Drug interactions represent a major issue in clinical settings, especially for critically ill patients such as those with cardiovascular disease (CVD) who require cardiothoracic surgery (CTS) and receive a high number of different medications.
Marios Spanakis   +4 more
doaj   +1 more source

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