Results 301 to 310 of about 5,634,975 (396)

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Chat GPT vs. Clinical Decision Support Systems in the Analysis of Drug-Drug Interactions. [PDF]

Clin Pharmacol Ther
Bischof T, Al Jalali V, Zeitlinger M, Jorda A, Hana M, Singeorzan KN, Riesenhuber N, Stemer G, Schoergenhofer C.   +8 more
europepmc   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Potential drug-drug interactions among geriatric oncology patients: a retrospective study in Saudi Arabia. [PDF]

BMC Geriatr
Alkathiri MA, Bamogaddam RF, Alhabshi HA, AlAjmi MN, Alashgaai AA, Assiri GA, Al Yami MS, Almohammed OA.   +7 more
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Assessment of Potential Drug-Drug Interactions of Psycholeptics and Antidepressants in Outpatient Settings. [PDF]

Pharmacy (Basel)
Marović I, Marinović I, Bačić Vrca V, Samardžić I.   +3 more
europepmc   +1 more source

Drug-Induced Ocular Side Effects and Drug Interactions

, 1977
Benjamin F. McGraw
openalex   +1 more source

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

FEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita, Toyonobu Usuki, Robert R. Kay, Tamao Saito   +3 more
wiley   +1 more source

Lack of Pharmacokinetic Drug-Drug Interactions Between Bepirovirsen and Nucleos(t)ide Analogs. [PDF]

Clin Pharmacol Drug Dev
Han K, Youssef AS, Magee M, Hood S, Tracey H, Kwoh J, Theodore D, Paff M, Nader A.   +8 more
europepmc   +1 more source

Interactions between psychotropic drugs and synaptosomes

, 1974
Ryoichi Ishitani, Ryoko Saito, Takio Iwamot   +2 more
openalex   +1 more source