Results 31 to 40 of about 5,634,975 (396)

Prevalence and Clinical Significance of Drug–Drug and Drug–Dietary Supplement Interactions among Patients Admitted for Cardiothoracic Surgery in Greece

Pharmaceutics, 2021
Background: Drug interactions represent a major issue in clinical settings, especially for critically ill patients such as those with cardiovascular disease (CVD) who require cardiothoracic surgery (CTS) and receive a high number of different medications.
Marios Spanakis, Maria Melissourgaki, George Lazopoulos, Athina E. Patelarou, Evridiki Patelarou   +4 more
doaj   +1 more source

Natural products in drug discovery: meeting the urgency for new antimicrobials for human and veterinary use

AIMS Molecular Science, 2023
The scenario of growing microbial resistance and of lack of interest of pharmaceutical companies in developing new antimicrobial drugs jeopardizes the present and the future of the treatment of infectious diseases.
Marcus Vinícius Dias-Souza, Arthur Azevedo Perpétuo, Gabriel Souza dos Santos, Luiz Felipe Carreiro Machado , Renan Martins dos Santos   +4 more
doaj   +1 more source

NOACs: drug–drug interactions [PDF]

Canadian Medical Association Journal, 2016
We commend Fralick and colleagues for their article on drug interactions with rivaroxaban.[1][1] All novel oral anticoagulants (NOACs) were introduced as at least noninferior (in some cases superior) to warfarin.
Mariusz Gasior, Andrzej Lekston, Bartosz Hudzik   +2 more
openaire   +2 more sources

A network inference method for large-scale unsupervised identification of novel drug-drug interactions [PDF]

, 2013
Characterizing interactions between drugs is important to avoid potentially harmful combinations, to reduce off-target effects of treatments and to fight antibiotic resistant pathogens, among others.
Guimera, Roger, Sales-Pardo, Marta
core   +4 more sources

Drug–Drug Interactions with Direct Oral Anticoagulants

Clinical Pharmacokinetics, 2020
A large body of evidence suggests that not only direct anticoagulant effects but also major bleeding events and stroke prevention depend on plasma concentrations of direct oral anticoagulants (DOACs).
K. Foerster, S. Hermann, G. Mikus, W. Haefeli   +3 more
semanticscholar   +1 more source

Neuronal stem cell-drug interactions : a systematic review and meta-analysis [PDF]

, 2019
Stem cell therapy is a promising treatment option for neurodegenerative diseases that mostly affect geriatric patients who often suffer from comorbidities requiring multiple medications.
Boltze, Johannes, Ikhsan, Maulana, Palumbo, Alex, Rose, Dorothee, Zille, Marietta   +4 more
core   +1 more source

Synergistic drug combinations from electronic health records and gene expression. [PDF]

, 2016
ObjectiveUsing electronic health records (EHRs) and biomolecular data, we sought to discover drug pairs with synergistic repurposing potential. EHRs provide real-world treatment and outcome patterns, while complementary biomolecular data, including ...
Chen, William, Daugherty, Aaron C, Desai, Manisha, Farrington, Carl, Gomez, Scarlett L, Hastie, Trevor, Kenkare, Pragati, Kurian, Allison W, Lim, Michael, Low, Yen S, Mathur, Maya, Radin, Andrew A, Schroeder, Elizabeth A, Seto, Tina, Shah, Nigam H, Sirota, Marina, Sledge, George W, Thompson, Caroline A, Weber, Susan, Yu, Peter P   +19 more
core   +2 more sources

Potential drug-drug interactions and prescription errors in COVID-19 infected patients

Public Health and Toxicology, 2023
Introduction Prescription errors can cause havoc during the pandemic, especially for comorbid patients with diabetes and hypertension identified as a risky population group for COVID-19.
Syeda R. Tasfia, Hujaifa A. Sakib, Tasmiah Khanam, Nazia Hoque, Mamunur Rahman, Arif Khan, Sufia Islam   +6 more
doaj   +1 more source

Provenance-Centered Dataset of Drug-Drug Interactions [PDF]

, 2015
Over the years several studies have demonstrated the ability to identify potential drug-drug interactions via data mining from the literature (MEDLINE), electronic health records, public databases (Drugbank), etc.
A Callahan, A Gottlieb, B Mons, DS Wishart, J Lazarou, K Haerian, L Zhang, M Dumontier, NP Tatonetti, P Avillach, P Groth, RL Bushardt, S Vilar, SV Iyer, T Kuhn   +14 more
core   +3 more sources

Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: A Pharmacokinetic, Microbiome, and Untargeted Metabolomics Study. [PDF]

, 2020
Determining factors that contribute to interindividual and intra-individual variability in pharmacokinetics (PKs) and drug metabolism is essential for the optimal use of drugs in humans.
Alhaja, Maher, Dorrestein, Pieter C, Jarmusch, Alan K, Knight, Rob, Liyanage, Marlon, Ma, Joseph D, Momper, Jeremiah D, Tsunoda, Shirley M, Vrbanac, Alison   +8 more
core   +1 more source