Results 51 to 60 of about 1,107,385 (201)

Drug Interactions of Metformin Involving Drug Transporter Proteins [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2017
Metformin is a most widely used medication all around the world to treat Type 2 diabetes mellitus. It is also found to be effective against various conditions including, Prediabetes, Gestational diabetes mellitus (GDM), Polycystic Ovarian Syndrome (PCOS),
Naina Mohamed Pakkir Maideen   +2 more
doaj   +1 more source

Effect of continuous phase drug concentration, evaporation and partitioning on transdermal drug permeation kinetics with lipophilic vehicles [PDF]

open access: yes, 2008
In this work the dependence of transdermal drug permeation kinetics on continuous phase drug concentration, partitioning between formulation phases, partitioning between stratum corneum and continuous oil phase and evaporation of volatile formulation ...
Reiser, Miriam Regina Luise
core   +1 more source

Potential Drug-drug Interactions in Intensive Care Units in Turkey: A Point Prevalence Study

open access: yes, 2023
Objective:Drug-drug interaction (DDI) is related with complications and diminished efficacy of medications throughout the treatment process. Intensive care units (ICU) involve patients who are at elevated risk of potential drug-drug interactions (pDDI ...
Melike Şeyda Dağdelen   +3 more
core   +1 more source

Local and global modes of drug action in biochemical networks

open access: yes, 2008
It becomes increasingly accepted that a shift is needed from the traditional target-based approach of drug development to an integrated perspective of drug action in biochemical systems. We here present an integrative analysis of the interactions between
Schwartz, Jean Marc; id_orcid   +4 more
core   +1 more source

Uncovering New Drug Properties in Target-Based Drug–Drug Similarity Networks

open access: yes, 2020
Despite recent advances in bioinformatics, systems biology, and machine learning, the accurate prediction of drug properties remains an open problem. Indeed, because the biological environment is a complex system, the traditional approach—based on ...
Mihai Udrescu   +6 more
core   +1 more source

DataSheet1_Opioid Drug-Drug-Drug Interactions and Unintentional Traumatic Injury: Screening to Detect Three-Way Drug Interaction Signals.docx

open access: yes, 2022
Growing evidence suggests that drug interactions may be responsible for much of the known association between opioid use and unintentional traumatic injury.
Sean Hennessy (277760)   +10 more
core   +1 more source

An ontology for drug-drug interactions [PDF]

open access: yes, 2014
Drug-drug interactions form a significant risk group for adverse effects associ-ated with pharmaceutical treatment. These interactions are often reported in the literature, however, they are sparsely represented in machine-readable re-sources, such as online databases, thesauri or ontologies.
María Herrero-Zazo   +5 more
openaire   +1 more source

Measuring drug similarity using drug–drug interactions

open access: yesQuantitative Biology
Combination therapy is a promising approach to address the challenge of antimicrobial resistance, and computational models have been proposed for predicting drug–drug interactions.
Ji Lv   +4 more
doaj   +1 more source

Evaluation of resources for analyzing drug interactions

open access: yesJournal of the Medical Library Association, 2017
Objective: The research sought to evaluate seven drug information resources, specifically designed for analyzing drug interactions for scope, completeness, and ease of use, and determine the consistency of content among the seven resources.
Risha I. Patel, Robert D. Beckett
doaj   +1 more source

Evaluation of Pharmacokinetic Drug–Drug Interactions: A Review of the Mechanisms, In Vitro and In Silico Approaches

open access: yes, 2021
Pharmacokinetic drug–drug interactions (DDIs) occur when a drug alters the absorption, transport, distribution, metabolism or excretion of a co-administered agent.
Yaru Peng, Feifan Xie, Zeneng Cheng
core   +1 more source

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