Results 61 to 70 of about 1,107,385 (201)

Associated factors of potential drug-drug interactions and drug–food interactions in patients with multiple sclerosis

Therapeutic Advances in Chronic Disease, 2022
Background: Multiple sclerosis (MS) is the most common immune-mediated demyelinating disease in younger adults. Patients with MS (PwMS) are vulnerable to the presence of potential drug–drug interactions (pDDIs) and potential drug–food interactions (pDFIs)
Jane Louisa Debus, Paula Bachmann, Niklas Frahm, Pegah Mashhadiakbar, Silvan Elias Langhorst, Barbara Streckenbach, Julia Baldt, Felicita Heidler, Michael Hecker, Uwe Klaus Zettl   +9 more
doaj   +1 more source

DeepDrug: A general graph‐based deep learning framework for drug‐drug interactions and drug‐target interactions prediction

Quantitative Biology, 2023
Computational methods for DDIs and DTIs prediction are essential for accelerating the drug discovery process. We proposed a novel deep learning method DeepDrug, to tackle these two problems within a unified framework.
Qijin Yin, Rui Fan, Xusheng Cao, Qiao Liu, Rui Jiang, Wanwen Zeng   +5 more
doaj   +1 more source

A pilot study to determine the occurrence of concomitant diseases and drug intake in patients on antituberculosis therapy

Journal of Family Medicine and Primary Care, 2018
Introduction: Altered pharmacokinetics of antituberculosis (anti-TB) drugs due to interaction with non-TB medications or concomitant diseases may lead to suboptimal plasma levels of the affected drugs and hence contribute to the emergence of drug ...
Ratinder Jhaj, Shweta Sharma, Mohammed Sabir, Arun Kokane   +3 more
doaj   +1 more source

DRUG-DRUG INTERACTIONS;

The Professional Medical Journal, 2014
Introduction: This research paper is based on a study conducted on the in-doorpatients at a teaching hospital in Gujrat, Pakistan, in order to check for the frequency with whichPenicillins, Quinolones and Cephalosporins are being used together and in combinations withother drugs and the drug-drug interactions that occur due to these combinations and ...
Syed Talat Iqbal, Zainab Batool, Haseeba Amir, Tamkenat Mansoor   +3 more
openaire   +3 more sources

Pilot study: Evaluation of potential drug–drug interactions in hospitalized pediatric patients

Pediatrics and Neonatology, 2020
Purpose: Evaluate the type and severity of potential drug-drug interactions and identify risk factors involved, in pediatric patients admitted in a hospital setting.
Fabiola Medina-Barajas, Estefanía Vázquez-Méndez, Edsaúl Emilio Pérez-Guerrero, Virginia Aleyda Sánchez-López, Iván I. Hernández-Cañaveral, Real-Ornelas Gabriel A, Selene G. Huerta-Olvera   +6 more
doaj   +1 more source

The pharmacogenetics of drug metabolizing enzymes in the Lebanese population [PDF]

, 2014
Drug metabolizing enzymes (DMEs) play a major role in the metabolism and final elimination of most drugs and xenobiotics from the body. Both phase I and phase II enzymes are highly polymorphic.
Khoueiry-Zgheib, Nathalie, Ossaily, Safaa   +1 more
core   +1 more source

Drug-drug interactions and potentially inappropriate medications among elderly outpatients

, 2021
The high prevalence of concomitant chronic illnesses and the resulting higher number of medications in the elderly population increase the risk of adverse drug reactions due to drug-drug interactions (DDIs) and potentially inappropriate medications (PIMs)
Kargar Mona (12681416), Javadi Mohammad Reza (12681419), Gholami Kheirollah (12681422), Rezaei Fatemeh (12681410), Atrianfar Fatemeh (12681407), Heidari Kazem (12681413)   +5 more
core   +1 more source

Conformational analysis of fenoterol stereoisomers

Current Issues in Pharmacy and Medical Sciences
Fenoterol is a relatively long-acting selective agonist of β2 adrenergic receptor (β2-AR) used in the treatment of asthma. Its molecule contains two stereogenic centers, thus, the compound exists as four stereoisomers.
Anita Płazińska, Joanna Olek, Krzysztof Jóźwiak   +2 more
doaj  

Gastroretentive microparticles for drug delivery applications [PDF]

, 2011
Many strategies have been proposed to explore the possibility of exploiting gastroretention for drug delivery. Such systems would be useful for local delivery, for drugs that are poorly soluble at higher pH or primarily absorbed from the proximal small ...
Conway, Barbara R, Barbara R. Conway, Adeola Adebisi, Adebisi, Adeola, Conway, Barbara R., Adebisi, Adeola O.   +5 more
core   +1 more source

Transporter-Mediated Drug–Drug Interactions with Oral Antidiabetic Drugs

Pharmaceutics, 2011
Uptake transporters (e.g., members of the SLC superfamily of solute carriers) and export proteins (e.g., members of the ABC transporter superfamily) are important determinants for the pharmacokinetics of drugs.
Jörg König, Martin F. Fromm, Sabine Klatt   +2 more
doaj   +1 more source