Results 141 to 150 of about 6,563,401 (267)
, 2014 September 25, 2014 From: Rex Buchanan, Interim Director, Kansas Geological Survey; Mike Tate, Chief, Bureau of Water, Dept. of Health and Environment; Ryan Hoffman, Director, Conservation Division, Corporation Commission; State Task Force on Induced ...
Kansas Induced Seismicity State Task Force.
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Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Effect of Herbal Extracts on Antituberculosis Drug-Induced Hepatotoxicity: A Systematic Review. [PDF]
J ToxicolRavedar SM +6 more
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Drug-Induced Lung Injury Masking Lung Adenocarcinoma. [PDF]
Respirol Case RepWatanabe K, Kamata T, Yoshida S, Sato T.
europepmc +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Current landscape of drug induced retinal vasculitis. [PDF]
J Ophthalmic Inflamm InfectMurugan SB +9 more
europepmc +1 more source
Chlorzoxazone-Induced Fixed Drug Eruption: A Clinical Case Report [PDF]
Hend Alotaibi,1 Reem Alsergani,1 Amer Abdulaziz Alharbi,1 Khalid Nabil Nagshabandi,1 Asma Ahmed Almubark2 1Department of Dermatology, College of Medicine, King Saud University, Riyadh, Saudi Arabia; 2College of Medicine, King Faisal University, Al-Ahsa ...
Alotaibi H +4 more
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Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source