Results 151 to 160 of about 6,563,401 (267)

Drug-induced neuropathies

Family Medicine & Primary Care Review, 2015
Marta Banach, Judyta K. Juranek, Jakub Antczak   +2 more
doaj   +1 more source

Association of the NOS1AP rs10494366 Genetic Variant With Drug-Induced QT Prolongation. [PDF]

Clin Transl Sci
Pippis CA, Lopez-Medina AI, Chahal CAA, Luzum JA.   +3 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

A diagnostic challenge: Life-threatening drug reaction with eosinophilia and systemic symptoms in the setting of a SARS-CoV-2 and human herpesvirus-6 reactivation in a patient with severe hepatic injury on bupropion

JAAD Case Reports, 2023
Djoni Elkady, BS, Chiamaka L. Okorie, BS, Blanca Estupiñan, MD, Mitul B. Modi, MD, Scott J. Cotler, MD, Eden Lake, MD   +5 more
doaj   +1 more source

Drug-Induced Enterocolitis Syndrome in Children: A Report of Two Cases. [PDF]

Cureus
Ferreira H, Capela J, Araújo AR, Teixeira F, Pinto D.   +4 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

A case of topical 5-fluorouracil provoked psoriasis

JAAD Case Reports, 2023
Kevin S. Puerta Durango, BSc, BA, Chiamaka L. Okorie, BSc, Shabnam Momtahen, MD, Brian J. Simmons, MD   +3 more
doaj   +1 more source

A Case of Drug-Induced Liver Injury Associated With Saw Palmetto. [PDF]

Cureus
Jayasree Rajendran R, Biscuitwala V, Vayalveettil AA, Singh Johal J.   +3 more
europepmc   +1 more source

Clinical factors predicting drug-induced liver injury due to flucloxacillin

, 2018
Mikaela Lindh,1 Pär Hallberg,1 Qun-Ying Yue,2 Mia Wadelius1 1Department of Medical Sciences, Clinical Pharmacology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden; 2Swedish Medical Products Agency, Uppsala, Sweden Objectives ...
Lindh M, Yue QY, Hallberg P, Wadelius M
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source