Results 171 to 180 of about 1,413,692 (298)

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source

Histopathological Changes as a Predictor of Fatal Outcome in Patients With Drug-Induced Liver Injury. [PDF]

Liver Int
Weber S, Erhardt F, Neumann J, Allgeier J, Saka D, Donga N, Mircheva I, Balakumar R, Lange CM, Gerbes AL.   +9 more
europepmc   +1 more source

Studies on Drug Metabolism. I. Effect of Respiratory Oxygen on the Duration of Pentobarbital induced Sleep

, 1968
Haruo Kitagawa
openalex   +2 more sources

THE INFLUENCE OF POSTNATAL DEVELOPMENT ON DRUG-INDUCED HEPATIC PORPHYRIA AND THE SYNTHESIS OF CYTOCHROME P-450 [PDF]

, 1971
Chull S. Song, Harold L. Moses, Alan S. Rosenthal, Nancy A. Gelb, Attallah Kappas   +4 more
openalex   +1 more source

A single gene mutation predicts response to immune checkpoint blockade in ovarian clear cell carcinoma

Molecular Oncology, EarlyView.
Loss‐of‐function mutations in the scaffold subunit of protein phosphatase 2A (PP2A), PPP2R1A, sensitize ovarian clear cell carcinoma to immune checkpoint blockade (ICB) by enhancing the interferon gamma response and promoting antitumor immune cell infiltration.
Matheus Henrique Dias, René Bernards
wiley   +1 more source

Drug-Induced Lichenoid Photosensitivity: A Case Report. [PDF]

Cureus
Raikar SR, Sneha S, G S, Rajkumar J.
europepmc   +1 more source

The effects of some drugs which induce agranulocytosis on the metabolism of separated human polymorphonuclear leucocytes and lymphocytes [PDF]

, 1970
Paul H. McCurrach, Judith K. Park, Walter L. Perry   +2 more
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Oxamniquine fever--drug-induced or immune-complex reaction? [PDF]

, 1979
Gene I. Higashi, Z. Farid
openalex   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source