Results 221 to 230 of about 1,413,692 (298)

Changes in Drug-Induced Hospitalisations and Deaths During the First Year of the COVID-19 Pandemic in Australia. [PDF]

Drug Alcohol Rev
Man N, Akhurst J, Price O, Chrzanowska A, Sutherland R, Dietze PM, Bruno R, Degenhardt L, Yuen WS, Moran L, Tierney L, Peacock A.   +11 more
europepmc   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Drug-Induced Liver Injury in Patients With Chronic Liver Disease. [PDF]

Liver Int
Ghabril M, Vuppalanchi R, Chalasani N.
europepmc   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

FDA's insights: implementing new strategies for evaluating drug-induced QTc prolongation. [PDF]

J Pharmacokinet Pharmacodyn
Ji Y, Johannesen L, Garnett C.
europepmc   +1 more source

Noise analysis of drug induced voltage clamp currents in denervated frog muscle fibres.

, 1976
Erwin Neher, B. Sakmann
openalex   +2 more sources

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Extensive pigmented abdominal plaque in a diabetic patient

JAAD Case Reports, 2021
Ahmed I. Mourad, BSc, MD, Ronald J. Sigal, MD, MPH, FRCPC, Richard M. Haber, MD, FRCPC   +2 more
doaj  

Drug-Induced Myoclonus: A Systematic Review. [PDF]

Medicina (Kaunas)
Rissardo JP, Fornari Caprara AL, Bhal N, Repudi R, Zlatin L, Walker IM.   +5 more
europepmc   +1 more source

Discontinuation of Immunotherapy in Patients With Relapsing Myelitis Without AQP4/MOG Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study assesses the outcomes of immunotherapy discontinuation in patients with relapsing seronegative idiopathic myelitis (SIM), a condition that remains uninvestigated due to its rarity. We reviewed records from 77 patients with relapsing SIM at the National Cancer Center of Korea, focusing on 11 who discontinued treatment after a median ...
Ki Hoon Kim, You‐Ri Kang, Jae‐Won Hyun, Su‐Hyun Kim, Ho Jin Kim   +4 more
wiley   +1 more source