Results 251 to 260 of about 10,944,767 (389)

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Drug-Induced Ultrastructural Alterations of Striated Muscles

, 1969
C. N. Sun, D. H. Bowden
openalex   +2 more sources

Stercoral perforation: case of drug-induced impaction. [PDF]

, 1978
A J Cass
openalex   +1 more source

Drug-Induced Sarcoidosis-Like Reactions.

Chest, 2018
A. Chopra, Amit Nautiyal, Alexander Kalkanis, M. Judson   +3 more
semanticscholar   +1 more source

Machine Learning-Enabled Drug-Induced Toxicity Prediction. [PDF]

Adv Sci (Weinh)
Bai C, Wu L, Li R, Cao Y, He S, Bo X.
europepmc   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Transcriptomic signature for drug-induced steatosis [PDF]

, 2015
Stoeber, Regina
core   +1 more source

Drug-Induced Liver Injury in Patients With Chronic Liver Disease. [PDF]

Liver Int
Ghabril M, Vuppalanchi R, Chalasani N.
europepmc   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Noise analysis of drug induced voltage clamp currents in denervated frog muscle fibres.

, 1976
Erwin Neher, B. Sakmann
openalex   +2 more sources